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Sfpq
Gene Detail
 Symbol
Name
ID
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
MGI:1918764
Synonyms 1110004P21Rik, 2810416M14Rik, 5730453G22Rik, 9030402K04Rik, D4Ertd314e, PSF, REP1
Feature Type protein coding gene
Genetic Map
Chromosome 4
61.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:127021324-127037013 bp, + strand
From VEGA annotation of GRCm38

  15690 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3714  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sfpq

Human
homologs
Human Homolog SFPQ, splicing factor proline/glutamine-rich
NCBI Gene ID 6421
neXtProt AC  NX_P23246
Human Synonyms  POMP100, PPP1R140, PSF
Human Chr (Location)  1p34.3; chr1:35176380-35193157 (-)  GRCh38
Alleles
and
phenotypes
All alleles(17) : Gene trapped(15) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trap allele die. Heterozygous mice show abnormality in entrainment of circadian rhythm.
 
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process alternative mRNA splicing, via spliceosome, cellular response to DNA damage stimulus, ...
Component cytoplasm, nuclear matrix, ...
Function core promoter binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (31)    Tissues (29)    Images (8)
Theiler Stages: 11, 13, 19, 21, 28
Assay TypeResults
RNA in situ 29
RT-PCR 2
cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(29) cDNA(27) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000009316 (Evidence)
Ensembl Gene ModelENSMUSG00000028820 (Evidence)
Entrez Gene71514 (Evidence)
Consensus CDS ProjectCCDS18662.1
International Mouse Knockout Project StatusSfpq
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009316 VEGA Gene Model | MGI Sequence Detail 15690 C57BL/6J ±  kb
transcript OTTMUST00000021160 VEGA | MGI Sequence Detail 3465 Not Applicable 
polypeptide OTTMUSP00000009684 VEGA | MGI Sequence Detail 699 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(7) UniProt(5)
Polymorphisms SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012975 NOPS
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000014743 splicing factor, proline- and glutamine-rich
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:199302 Veenvliet JV, et al., Specification of dopaminergic subsets involves interplay of En1 and Pitx3. Development. 2013 Aug;140(16):3373-84
All references(49)
Other
accession IDs
MGI:1196226, MGI:1915728, MGI:1917845, MGI:1925565, MGI:2140463

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory