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Krtap2-4 Gene Detail
Summary
  • Symbol
    Krtap2-4
  • Name
    keratin associated protein 2-4
  • Synonyms
    5530401P19Rik, KAP2.4, KRTAP2.4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918703
    NCBI Gene: 71453
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99614019-99614846 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 62.96 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918703
protein coding gene Chr11:99614017-99614846 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019105
protein coding gene Chr11:102295046-102296886 (-)
A/J MGP_AJ_G0019075
protein coding gene Chr11:97990560-97996800 (-)
AKR/J MGP_AKRJ_G0019045
protein coding gene Chr11:101024105-101024946 (-)
BALB/cJ MGP_BALBcJ_G0019047
protein coding gene Chr11:98494840-98496022 (-)
C3H/HeJ MGP_C3HHeJ_G0018861
protein coding gene Chr11:101184070-101184911 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019497
protein coding gene Chr11:105429604-105431923 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017132
protein coding gene Chr11:95543724-95544545 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0018834
protein coding gene Chr11:109823888-109827457 (-)
DBA/2J MGP_DBA2J_G0018940
protein coding gene Chr11:97561155-97562105 (-)
FVB/NJ MGP_FVBNJ_G0018931
protein coding gene Chr11:97059336-97060177 (-)
LP/J MGP_LPJ_G0019011
protein coding gene Chr11:102763740-102764581 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018958
protein coding gene Chr11:109488782-109489623 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019539
protein coding gene Chr11:101393787-101394781 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0017974
protein coding gene Chr11:101134291-101134925 (+)
WSB/EiJ MGP_WSBEiJ_G0018466
protein coding gene Chr11:101356737-101358116 (-)



Homology
more
  • Human Ortholog
    KRTAP2-3, keratin associated protein 2-3
  • Vertebrate Orthologs
    21
  • Human Ortholog
    KRTAP2-3, keratin associated protein 2-3
    Orthology source: HomoloGene
  • Synonyms
    KAP2.3, KAP2.4, KRTAP2.3, KRTAP2-4, KRTAP2.4
  • Links
    NCBI Gene ID: 730755
    neXtProt AC: NX_P0C7H8, NX_Q9BYR9
    UniProt: P0C7H8

  • Chr Location
    chr17:41059240-41060092 (-)  GRCh38.p7

  • Human Ortholog
    KRTAP2-4, keratin associated protein 2-4
    Orthology source: HomoloGene
  • Synonyms
    KAP2.1B, KAP2.3, KAP2.4, KRTAP2-3, KRTAP2.3, KRTAP2.4
  • Links
    NCBI Gene ID: 85294
    neXtProt AC: NX_P0C7H8, NX_Q9BYR9
    UniProt: Q9BYR9

  • Chr Location
    17q21.2; chr17:41065116-41065879 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060756 Ensembl Gene Model | MGI Sequence Detail 828 C57BL/6J ±  kb
transcript ENSMUST00000074926 Ensembl | MGI Sequence Detail 828 Not Applicable  
polypeptide ENSMUSP00000074461 Ensembl | MGI Sequence Detail 131 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Phenotypes 6
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory