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Mettl13 Gene Detail
Summary
  • Symbol
    Mettl13
  • Name
    methyltransferase like 13
  • Synonyms
    5630401D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918699
    NCBI Gene: 71449
  • Gene Overview
    MyGene.info: EEF1AKNMT
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162533671-162548345 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 70.29 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918699
protein coding gene Chr1:162532127-162548551 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016659
protein coding gene Chr1:167864757-167881182 (-)
A/J MGP_AJ_G0016640
protein coding gene Chr1:161031768-161048192 (-)
AKR/J MGP_AKRJ_G0016606
protein coding gene Chr1:165914616-165931040 (-)
BALB/cJ MGP_BALBcJ_G0016601
protein coding gene Chr1:161563185-161579614 (-)
C3H/HeJ MGP_C3HHeJ_G0016425
protein coding gene Chr1:166124935-166141359 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017062
protein coding gene Chr1:173524326-173540749 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014771
protein coding gene Chr1:153088119-153104723 (-)
CAST/EiJ MGP_CASTEiJ_G0016005
protein coding gene Chr1:165774554-165791032 (-)
CBA/J MGP_CBAJ_G0016400
protein coding gene Chr1:179703554-179719979 (-)
DBA/2J MGP_DBA2J_G0016506
protein coding gene Chr1:159974304-159990755 (-)
FVB/NJ MGP_FVBNJ_G0016504
protein coding gene Chr1:158407330-158423753 (-)
LP/J MGP_LPJ_G0016577
protein coding gene Chr1:168986300-169008625 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016529
protein coding gene Chr1:187217908-187234230 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017098
protein coding gene Chr1:165746524-165762938 (-)
PWK/PhJ MGP_PWKPhJ_G0015791
protein coding gene Chr1:159154891-159171675 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015578
protein coding gene Chr1:164638323-164654531 (-)
WSB/EiJ MGP_WSBEiJ_G0016067
protein coding gene Chr1:165929934-165946358 (-)



Homology
more
  • Human Ortholog
    EEF1AKNMT, eEF1A lysine and N-terminal methyltransferase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EEF1AKNMT, eEF1A lysine and N-terminal methyltransferase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    5630401D24Rik, CGI-01, DFNB26, DFNB26M, feat, KIAA0859, METTL13
  • Links
    NCBI Gene ID: 51603
    neXtProt AC: NX_Q8N6R0
    UniProt: Q8N6R0

  • Chr Location
    1q24.3; chr1:171781504-171823962 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71449 NCBI Gene Model | MGI Sequence Detail 14675 C57BL/6J ±  kb
transcript NM_144877 RefSeq | MGI Sequence Detail 2801 FVB/N  
polypeptide Q91YR5 UniProt | EBI | MGI Sequence Detail 698 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 7
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:261178 Yousaf R, et al., Modifier variant of METTL13 suppresses human GAB1-associated profound deafness. J Clin Invest. 2018 Apr 2;128(4):1509-1522

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory