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Dhrs2 Gene Detail
Summary
  • Symbol
    Dhrs2
  • Name
    dehydrogenase/reductase member 2
  • Synonyms
    5430405K24Rik, SDR family
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918662
    NCBI Gene: 71412
  • Gene Overview
    MyGene.info: DHRS2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55222007-55241435 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 28.12 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    152 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918662
protein coding gene Chr14:55222007-55241440 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021342
protein coding gene Chr14:49230782-49248467 (+)
A/J MGP_AJ_G0021301
protein coding gene Chr14:48245449-48264912 (+)
AKR/J MGP_AKRJ_G0021277
protein coding gene Chr14:50000202-50019616 (+)
BALB/cJ MGP_BALBcJ_G0021305
protein coding gene Chr14:48219478-48235267 (+)
C3H/HeJ MGP_C3HHeJ_G0021085
protein coding gene Chr14:49692782-49712136 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021743
protein coding gene Chr14:51722161-51738849 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019290
protein coding gene Chr14:46644403-46659407 (+)
CAST/EiJ MGP_CASTEiJ_G0020604
protein coding gene Chr14:45947386-45962642 (+)
CBA/J MGP_CBAJ_G0021052
protein coding gene Chr14:53277893-53297270 (+)
DBA/2J MGP_DBA2J_G0021173
protein coding gene Chr14:47988900-48007400 (+)
FVB/NJ MGP_FVBNJ_G0021155
protein coding gene Chr14:47453223-47470376 (+)
LP/J MGP_LPJ_G0021247
protein coding gene Chr14:50283162-50298979 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021179
protein coding gene Chr14:52636860-52653010 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021770
protein coding gene Chr14:49181861-49198671 (+)
PWK/PhJ MGP_PWKPhJ_G0020351
protein coding gene Chr14:44525045-44541584 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020179
protein coding gene Chr14:45177209-45192263 (+)
WSB/EiJ MGP_WSBEiJ_G0020657
protein coding gene Chr14:49477901-49494475 (+)



Homology
more
  • Human Ortholog
    DHRS2, dehydrogenase/reductase 2
  • Vertebrate Orthologs
    3
  • Human Ortholog
    DHRS2, dehydrogenase/reductase 2
    Orthology source: HGNC
  • Synonyms
    HEP27, SDR25C1
  • Links
    NCBI Gene ID: 10202
    neXtProt AC: NX_Q13268
    UniProt: Q13268

  • Chr Location
    14q11.2; chr14:23630115-23645639 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022209 Ensembl Gene Model | MGI Sequence Detail 19429 C57BL/6J ±  kb
transcript ENSMUST00000022820 Ensembl | MGI Sequence Detail 1268 Not Applicable  
polypeptide ENSMUSP00000022820 Ensembl | MGI Sequence Detail 282 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR036291 NAD(P)-binding domain superfamily
    IPR020904 Short-chain dehydrogenase/reductase, conserved site
    IPR002347 Short-chain dehydrogenase/reductase SDR
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory