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Fmnl2 Gene Detail
Summary
  • Symbol
    Fmnl2
  • Name
    formin-like 2
  • Synonyms
    5430425K04Rik, man
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918659
    NCBI Gene: 71409
  • Gene Overview
    MyGene.info: FMNL2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:52857860-53133804 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 30.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1400 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918659
protein coding gene Chr2:52857717-53134202 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025737
protein coding gene Chr2:52227979-52522841 (+)
A/J MGP_AJ_G0025713
protein coding gene Chr2:50201723-50480872 (+)
AKR/J MGP_AKRJ_G0025683
protein coding gene Chr2:51633469-51925855 (+)
BALB/cJ MGP_BALBcJ_G0025708
protein coding gene Chr2:50305761-50585731 (+)
C3H/HeJ MGP_C3HHeJ_G0025469
protein coding gene Chr2:51655422-51950258 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026154
protein coding gene Chr2:53754447-54047557 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023560
protein coding gene Chr2:48170956-48450802 (+)
CAST/EiJ MGP_CASTEiJ_G0024934
protein coding gene Chr2:51760325-52068315 (+)
CBA/J MGP_CBAJ_G0025449
protein coding gene Chr2:55801482-56104771 (+)
DBA/2J MGP_DBA2J_G0025580
protein coding gene Chr2:49845619-50127161 (+)
FVB/NJ MGP_FVBNJ_G0025542
protein coding gene Chr2:49534216-49813970 (+)
LP/J MGP_LPJ_G0025668
protein coding gene Chr2:52124679-52423111 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025573
protein coding gene Chr2:56799335-57101751 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026212
protein coding gene Chr2:51572693-51860372 (+)
PWK/PhJ MGP_PWKPhJ_G0024675
protein coding gene Chr2:49732694-50016239 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024481
protein coding gene Chr2:51773268-52089767 (+)
WSB/EiJ MGP_WSBEiJ_G0025001
protein coding gene Chr2:51850535-52149801 (+)



Homology
more
  • Human Ortholog
    FMNL2, formin like 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FMNL2, formin like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FHOD2
  • Links
    NCBI Gene ID: 114793
    neXtProt AC: NX_Q96PY5
    UniProt: Q96PY5

  • Chr Location
    2q23.3; chr2:152335170-152649834 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036053 Ensembl Gene Model | MGI Sequence Detail 275945 C57BL/6J ±  kb
transcript ENSMUST00000090952 Ensembl | MGI Sequence Detail 5414 Not Applicable  
polypeptide ENSMUSP00000088472 Ensembl | MGI Sequence Detail 1091 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 67
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226856 Dutta P, et al., Expression of multiple formins in adult tissues and during developmental stages of mouse brain. Gene Expr Patterns. 2015 Sep-Nov;19(1-2):52-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory