Pex1
Gene Detail

Symbol Name ID

Pex1 peroxisomal biogenesis factor 1 MGI:1918632

Synonyms

5430414H02Rik, E330005K07Rik, peroxisome biogenesis factor 1, ZWS1

Feature Type

protein coding gene

Genetic Map

Chromosome 5

2.26 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:3596066-3637232 bp, + strand From VEGA annotation of GRCm38   41167 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:27006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Pex1

Human homologs

Human Homolog		PEX1, peroxisomal biogenesis factor 1
NCBI Gene ID		5189
neXtProt AC		NX_O43933
Human Synonyms		PBD1A, PBD1B, ZWS, ZWS1
Human Chr (Location)		7q21.2; chr7:92116337-92157845 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PEX1

Alleles and phenotypes

All alleles(5) : Targeted(2) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (23 annotations)

Process	microtubule-based peroxisome localization, peroxisome organization, ...
Component	cytoplasm, cytosol, ...
Function	ATPase activity, coupled, ATP binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(10)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000028545 (Evidence)
Ensembl Gene Model	ENSMUSG00000005907 (Evidence)
Entrez Gene	71382 (Evidence)
NIA Mouse Gene Index	U025929
PDB	1WLF
Consensus CDS Project	CCDS19065.1
International Mouse Knockout Project Status	Pex1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028545	VEGA Gene Model | MGI Sequence Detail	41167	C57BL/6J
transcript	OTTMUST00000070783	VEGA | MGI Sequence Detail	4555	Not Applicable
polypeptide	OTTMUSP00000036123	VEGA | MGI Sequence Detail	1284	Not Applicable

All sequences(47) RefSeq(3) UniProt(6)

Polymorphisms

SNPs(163 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003593	AAA+ ATPase domain
InterPro	IPR009010	Aspartate decarboxylase-like fold
InterPro	IPR003960	ATPase, AAA-type, conserved site
InterPro	IPR003959	ATPase, AAA-type, core
InterPro	IPR025653	Peroxisome biogenesis factor 1
InterPro	IPR015343	Peroxisome biogenesis factor 1, alpha/beta
InterPro	IPR015342	Peroxisome biogenesis factor 1, N-terminal
Protein Ontology	PR:000012553	peroxisome biogenesis factor 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:176132 O'Leary J, et al., Global analysis of gene expression in the developing brain of gtf2ird1 knockout mice. PLoS One. 2011;6(8):e23868
All references(34)

Other accession IDs

MGI:2444380