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Tmem74b Gene Detail
Summary
  • Symbol
    Tmem74b
  • Name
    transmembrane protein 74B
  • Synonyms
    5430405G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918629
    NCBI Gene: 108832
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:151702008-151712157 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 74.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    155 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918629
protein coding gene Chr2:151700946-151716412 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026644
protein coding gene Chr2:156195185-156205467 (+)
A/J MGP_AJ_G0026610
protein coding gene Chr2:149984226-149994373 (+)
AKR/J MGP_AKRJ_G0026580
protein coding gene Chr2:154350962-154361099 (+)
BALB/cJ MGP_BALBcJ_G0026619
protein coding gene Chr2:150294239-150304354 (+)
C3H/HeJ MGP_C3HHeJ_G0026362
protein coding gene Chr2:154740923-154751036 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027068
protein coding gene Chr2:160760758-160770887 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024439
protein coding gene Chr2:143600266-143610522 (+)
CAST/EiJ MGP_CASTEiJ_G0025823
protein coding gene Chr2:154968533-154978800 (+)
CBA/J MGP_CBAJ_G0026340
protein coding gene Chr2:166631260-166641395 (+)
DBA/2J MGP_DBA2J_G0026476
protein coding gene Chr2:149199056-149209199 (+)
FVB/NJ MGP_FVBNJ_G0026441
protein coding gene Chr2:147643109-147653252 (+)
LP/J MGP_LPJ_G0026580
protein coding gene Chr2:156366403-156376705 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026463
protein coding gene Chr2:170797709-170807786 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027123
protein coding gene Chr2:154233264-154243354 (+)
PWK/PhJ MGP_PWKPhJ_G0025557
protein coding gene Chr2:148724797-148734997 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025360
protein coding gene Chr2:153069018-153080521 (+)
WSB/EiJ MGP_WSBEiJ_G0025893
protein coding gene Chr2:155144357-155155415 (+)



Homology
more
  • Human Ortholog
    TMEM74B, transmembrane protein 74B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM74B, transmembrane protein 74B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf46
  • Links
    NCBI Gene ID: 55321
    neXtProt AC: NX_Q9NUR3
    UniProt: Q9NUR3

  • Chr Location
    20p13; chr20:1180561-1188138 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Tmem74b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044364 Ensembl Gene Model | MGI Sequence Detail 10150 C57BL/6J ±  kb
transcript ENSMUST00000060196 Ensembl | MGI Sequence Detail 1435 Not Applicable  
polypeptide ENSMUSP00000060017 Ensembl | MGI Sequence Detail 232 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR029695 Transmembrane protein 74-like
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory