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Rcbtb1 Gene Detail
Summary
  • Symbol
    Rcbtb1
  • Name
    regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
  • Synonyms
    5430409I18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918580
    NCBI Gene: 71330
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:59438658-59474714 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 31.47 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    87 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918580
protein coding gene Chr14:59438471-59474716 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021419
protein coding gene Chr14:53485085-53521146 (+)
A/J MGP_AJ_G0021380
protein coding gene Chr14:52370815-52406812 (+)
AKR/J MGP_AKRJ_G0021355
protein coding gene Chr14:54181739-54220775 (+)
BALB/cJ MGP_BALBcJ_G0021383
protein coding gene Chr14:52303808-52340626 (+)
C3H/HeJ MGP_C3HHeJ_G0021162
protein coding gene Chr14:53859958-53910076 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021822
protein coding gene Chr14:56061375-56103229 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019361
protein coding gene Chr14:50404976-50442687 (+)
CAST/EiJ MGP_CASTEiJ_G0020680
protein coding gene Chr14:50214789-50253203 (+)
CBA/J MGP_CBAJ_G0021129
protein coding gene Chr14:57718468-57763993 (+)
DBA/2J MGP_DBA2J_G0021250
protein coding gene Chr14:52028624-52067960 (+)
FVB/NJ MGP_FVBNJ_G0021231
protein coding gene Chr14:51426137-51480946 (+)
LP/J MGP_LPJ_G0021325
protein coding gene Chr14:54504765-54544279 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021259
protein coding gene Chr14:57105462-57144663 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021846
protein coding gene Chr14:53350015-53390911 (+)
PWK/PhJ MGP_PWKPhJ_G0020423
protein coding gene Chr14:48589078-48624133 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020256
protein coding gene Chr14:49421001-49457901 (+)
WSB/EiJ MGP_WSBEiJ_G0020732
protein coding gene Chr14:53672496-53709077 (+)



Homology
more
  • Human Ortholog
    RCBTB1, RCC1 and BTB domain containing protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RCBTB1, RCC1 and BTB domain containing protein 1
  • Synonyms
    CLLD7, CLLL7, GLP, RDEOA
  • Links
    NCBI Gene ID: 55213
    neXtProt AC: NX_Q8NDN9
    UniProt: Q8NDN9

  • Chr Location
    13q14.2; chr13:49531946-49585558 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    41
  • Chemically induced (other)
    1
  • Gene trapped
    37
  • Targeted
    3
  • Genomic Mutations
    1 involving Rcbtb1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035469 Ensembl Gene Model | MGI Sequence Detail 36057 C57BL/6J ±  kb
transcript ENSMUST00000043227 Ensembl | MGI Sequence Detail 3903 Not Applicable  
polypeptide ENSMUSP00000037030 Ensembl | MGI Sequence Detail 531 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000013832 RCC1 and BTB domain-containing protein 1
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR047996 RCC1 and BTB domain-containing protein 1, BTB/POZ domain
    IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
    IPR000408 Regulator of chromosome condensation, RCC1
    IPR011333 SKP1/BTB/POZ domain superfamily
Molecular
Reagents
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  • All nucleic 76
    cDNA 76

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145800
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory