Arhgap26
Gene Detail

Symbol Name ID

Arhgap26 Rho GTPase activating protein 26 MGI:1918552

Synonyms

1810044B20Rik, 2610010G17Rik, 4933432P15Rik, mKIAA0621

Feature Type

protein coding gene

Genetic Map

Chromosome 18

20.51 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr18:38601534-39376284 bp, + strand From VEGA annotation of GRCm38   774751 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:36349  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: Rho GTPase-activating protein, Oligophrenin 1/Graf types
Gene Tree: Arhgap26

Human homologs

Human Homolog		ARHGAP26, Rho GTPase activating protein 26
NCBI Gene ID		23092
neXtProt AC		NX_Q9UNA1
Human Synonyms		GRAF, GRAF1, OPHN1L, OPHN1L1
Human Chr (Location)		5q31; chr5:142150292-142608572 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ARHGAP26

Alleles and phenotypes

All alleles(17) : Targeted(3) Gene trapped(14)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	filopodium assembly, positive regulation of GTPase activity, ...
Component	cell junction, cytoplasm, ...
Function	cytoskeletal adaptor activity, GTPase activator activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (5)    Images (14)
Theiler Stages: 23

Assay Type	Results
RNA in situ	24

cDNA source data(38)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(40) cDNA(40)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000020314 (Evidence)
Ensembl Gene Model	ENSMUSG00000036452 (Evidence)
Entrez Gene	71302 (Evidence)
UniGene	329396
DFCI	TC1585958, TC1591357, TC1601980, TC1622875, TC1639922, TC1640293
DoTS	DT.101351422, DT.40181046, DT.55122533, DT.55182114, DT.55232876, DT.91331633
NIA Mouse Gene Index	U043670
Consensus CDS Project	CCDS29205.1
International Mouse Knockout Project Status	Arhgap26

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020314	VEGA Gene Model | MGI Sequence Detail	774751	C57BL/6J
transcript	OTTMUST00000048196	VEGA | MGI Sequence Detail	7898	Not Applicable
polypeptide	OTTMUSP00000022023	VEGA | MGI Sequence Detail	814	Not Applicable

All sequences(91) RefSeq(2) UniProt(11)

Polymorphisms

SNPs(2235 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013606	IRSp53/MIM homology domain (IMD)
InterPro	IPR001849	Pleckstrin homology domain
InterPro	IPR011993	Pleckstrin homology-like domain
InterPro	IPR000198	Rho GTPase-activating protein domain
InterPro	IPR008936	Rho GTPase activation protein
InterPro	IPR001452	Src homology-3 domain
Protein Ontology	PR:000004232	rho GTPase-activating protein 26

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:180006 Yokoyama K, et al., NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54
All references(34)

Other accession IDs

MGI:1917050, MGI:1917571, MGI:2147280