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Arhgap26
Gene Detail
 Symbol
Name
ID
Arhgap26
Rho GTPase activating protein 26
MGI:1918552
Synonyms 1810044B20Rik, 2610010G17Rik, 4933432P15Rik, mKIAA0621
Feature Type protein coding gene
Genetic Map
Chromosome 18
20.51 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:38601534-39376284 bp, + strand
From VEGA annotation of GRCm38

  774751 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36349  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: Rho GTPase-activating protein, Oligophrenin 1/Graf types
Gene Tree: Arhgap26

Human
homologs
Human Homolog ARHGAP26, Rho GTPase activating protein 26
NCBI Gene ID 23092
neXtProt AC  NX_Q9UNA1
Human Synonyms  GRAF, GRAF1, OPHN1L, OPHN1L1
Human Chr (Location)  5q31; chr5:142770378-143229007 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ARHGAP26
Alleles
and
phenotypes
All alleles(17) : Gene trapped(14) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process filopodium assembly, signal transduction
Component cell junction, cytoplasm, ...
Function cytoskeletal adaptor activity, GTPase activator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (5)    Images (14)
Theiler Stages: 23
Assay TypeResults
RNA in situ 24
cDNA source data(38)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(40) cDNA(40)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000020314 (Evidence)
Ensembl Gene ModelENSMUSG00000036452 (Evidence)
Entrez Gene71302 (Evidence)
UniGene329396
DFCITC1585958, TC1591357, TC1601980, TC1622875, TC1639922, TC1640293
DoTSDT.101351422, DT.40181046, DT.55122533, DT.55182114, DT.55232876, DT.91331633
NIA Mouse Gene IndexU043670
Consensus CDS ProjectCCDS29205.1
International Mouse Knockout Project StatusArhgap26
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020314 VEGA Gene Model | MGI Sequence Detail 774751 C57BL/6J ±  kb
transcript OTTMUST00000048196 VEGA | MGI Sequence Detail 7898 Not Applicable 
polypeptide OTTMUSP00000022023 VEGA | MGI Sequence Detail 814 Not Applicable 

For the selected sequences
All sequences(105) RefSeq(16) UniProt(11)
Polymorphisms SNPs within 2kb(5916 from dbSNP Build 137)    SNPs within 2kb including multiple locations(5926)
Protein-related
information
ResourceIDDescription
InterPro IPR013606 IRSp53/MIM homology domain (IMD)
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR000198 Rho GTPase-activating protein domain
InterPro IPR008936 Rho GTPase activation protein
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000004232 rho GTPase-activating protein 26
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:180006 Yokoyama K, et al., NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54
All references(35)
Other
accession IDs
MGI:1917050, MGI:1917571, MGI:2147280

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory