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Nbas Gene Detail
Summary
  • Symbol
    Nbas
  • Name
    neuroblastoma amplified sequence
  • Synonyms
    4933425L03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918419
    NCBI Gene: 71169
Location & Maps
more
  • Sequence Map
    Chr12:13269127-13583810 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      314684 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NBAS, neuroblastoma amplified sequence
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NBAS, neuroblastoma amplified sequence
    Orthology source: HGNC, HomoloGene
  • Synonyms
    NAG, SOPH
  • Links
    NCBI Gene ID: 51594
    neXtProt AC: NX_A2RRP1

  • Chr Location
    2p24; chr2:15166908-15561348 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41073
    1 human;1 mouse;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: NBAS
  • Gene Tree
Human Diseases
more
  • Diseases
    2 with human NBAS associations

Human Disease Mouse Models
       Infantile Liver Failure Syndrome 2; ILFS2   OMIM: 616483
Short Stature, Optic Nerve Atrophy, and Pelger-Huet Anomaly; SOPH   OMIM: 614800
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020576 Ensembl Gene Model | MGI Sequence Detail 314684 C57BL/6J ±  kb
transcript ENSMUST00000042953 Ensembl | MGI Sequence Detail 7239 Not Applicable  
polypeptide ENSMUSP00000036082 Ensembl | MGI Sequence Detail 2356 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1374 from dbSNP Build 137
Protein
Information
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  • UniProt
    8 Sequences
  • InterPro Domains
    IPR029145 Neuroblastoma-amplified sequence, N-terminal
    IPR011044 Quinoprotein amine dehydrogenase, beta chain-like
    IPR013244 Sec39 domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 78
    cDNA 78

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory