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Mier1 Gene Detail
Summary
  • Symbol
    Mier1
  • Name
    MEIR1 treanscription regulator
  • Synonyms
    4933425I22Rik, 5830411K19Rik, mKIAA1610
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918398
    NCBI Gene: 71148
  • Gene Overview
    MyGene.info: MIER1
Location & Maps
more
  • Sequence Map
    Chr4:103114390-103165754 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      51365 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MIER1, MIER1 transcriptional regulator
  • Vertebrate Orthologs
    4
  • Human Ortholog
    MIER1, MIER1 transcriptional regulator
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ER1, MI-ER1
  • Links
    NCBI Gene ID: 57708
    neXtProt AC: NX_Q8N108

  • Chr Location
    1p31.3; chr1:66924895-66988619 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    53
  • Chemically induced (other)
    2
  • Gene trapped
    47
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Mier1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008075 VEGA Gene Model | MGI Sequence Detail 51365 C57BL/6J ±  kb
transcript OTTMUST00000042372 VEGA | MGI Sequence Detail 4698 Not Applicable  
polypeptide OTTMUSP00000019044 VEGA | MGI Sequence Detail 556 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    213 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923268
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory