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Oxsm
Gene Detail
 Symbol
Name
ID
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
MGI:1918397
Synonyms 4933425A18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
7.08 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:16238656-16249808 bp, - strand
From VEGA annotation of GRCm38

  11153 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5820  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: KAS_II
Gene Tree: Oxsm

Human
homologs
Human Homolog OXSM, 3-oxoacyl-ACP synthase, mitochondrial
NCBI Gene ID 54995
neXtProt AC  NX_Q9NWU1
Human Synonyms  FASN2D, KASI, KS
Human Chr (Location)  3p24.2; chr3:25790072-25794534 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(3) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Oxsm interacts with 230 markers (Mir7-2, Mir7b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process acyl-CoA metabolic process, fatty acid biosynthetic process, ...
Component mitochondrion
Function 3-oxoacyl-[acyl-carrier-protein] synthase activity, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (1)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(20)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(21) Primer pair(1)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000023282 (Evidence)
Ensembl Gene ModelENSMUSG00000021786 (Evidence)
Entrez Gene71147 (Evidence)
UniGene197960
DFCITC1582719, TC1595693, TC1666089
DoTSDT.40166437, DT.55281822, DT.91372520, DT.94295501
NIA Mouse Gene IndexU035256
EC2.3.1.41
Consensus CDS ProjectCCDS26831.1
International Mouse Knockout Project StatusOxsm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023282 VEGA Gene Model | MGI Sequence Detail 11153 C57BL/6J ±  kb
transcript OTTMUST00000056369 VEGA | MGI Sequence Detail 3755 Not Applicable 
polypeptide OTTMUSP00000027084 VEGA | MGI Sequence Detail 459 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2
InterPro IPR018201 Beta-ketoacyl synthase, active site
InterPro IPR014031 Beta-ketoacyl synthase, C-terminal
InterPro IPR014030 Beta-ketoacyl synthase, N-terminal
InterPro IPR016039 Thiolase-like
InterPro IPR016038 Thiolase-like, subgroup
Protein Ontology PR:000012098 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2145866

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory