Oxsm
Gene Detail

Symbol Name ID

Oxsm 3-oxoacyl-ACP synthase, mitochondrial MGI:1918397

Synonyms

4933425A18Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 14

7.08 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr14:16238656-16249808 bp, - strand From VEGA annotation of GRCm38   11153 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5820  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: KAS_II
Gene Tree: Oxsm

Human homologs

Human Homolog		OXSM, 3-oxoacyl-ACP synthase, mitochondrial
NCBI Gene ID		54995
neXtProt AC		NX_Q9NWU1
Human Synonyms		FASN2D, KASI, KS
Human Chr (Location)		3p24.2; chr3:25831563-25836025 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(1) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	acyl-CoA metabolic process, fatty acid biosynthetic process, ...
Component	cytoplasm, mitochondrion
Function	3-oxoacyl-[acyl-carrier-protein] synthase activity, catalytic activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (1)
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) cDNA(22) Primer pair(1)
Microarray probesets(9)

Other database links

VEGA Gene Model	OTTMUSG00000023282 (Evidence)
Ensembl Gene Model	ENSMUSG00000021786 (Evidence)
Entrez Gene	71147 (Evidence)
UniGene	197960
DFCI	TC1582719, TC1595693, TC1666089
DoTS	DT.40166437, DT.55281822, DT.91372520, DT.94295501
NIA Mouse Gene Index	U035256
EC	2.3.1.41
Consensus CDS Project	CCDS26831.1
International Mouse Knockout Project Status	Oxsm

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023282	VEGA Gene Model | MGI Sequence Detail	11153	C57BL/6J
transcript	OTTMUST00000056372	VEGA | MGI Sequence Detail	2206	Not Applicable
polypeptide	OTTMUSP00000027087	VEGA | MGI Sequence Detail	459	Not Applicable

All sequences(43) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(51 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017568	3-oxoacyl-[acyl-carrier-protein] synthase 2
InterPro	IPR018201	Beta-ketoacyl synthase, active site
InterPro	IPR014031	Beta-ketoacyl synthase, C-terminal
InterPro	IPR014030	Beta-ketoacyl synthase, N-terminal
InterPro	IPR016039	Thiolase-like
InterPro	IPR016038	Thiolase-like, subgroup
Protein Ontology	PR:000012098	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGI:2145866