Rbbp5
Gene Detail

Symbol Name ID

Rbbp5 retinoblastoma binding protein 5 MGI:1918367

Synonyms

4933411J24Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 1

57.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:132477367-132505665 bp, + strand From NCBI annotation of GRCm38   28299 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3709  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rbbp5

Human homologs

Human Homolog		RBBP5, retinoblastoma binding protein 5
NCBI Gene ID		5929
neXtProt AC		NX_Q15291
Human Synonyms		RBQ3, SWD1
Human Chr (Location)		1q32; chr1:205055270-205091150 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(57) : Gene trapped(57)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	chromatin modification, histone H3-K4 methylation, ...
Component	histone methyltransferase complex, MLL1 complex, ...
Function	histone methyltransferase activity (H3-K4 specific), methylated histone residue binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (15)    Images (2)
Theiler Stages: 23

Assay Type	Results
RNA in situ	24

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) cDNA(14)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000026439 (Evidence)
Entrez Gene	213464 (Evidence)
DFCI	TC1579017, TC1583740, TC1698130, TC1762016
DoTS	DT.101313945, DT.101383715, DT.110531116, DT.55280555, DT.97360570
NIA Mouse Gene Index	U000803, U338720
PDB	2XL2, 2XL3
Consensus CDS Project	CCDS15286.1
International Mouse Knockout Project Status	Rbbp5

Sequences

Length	Strain/Species
genomic	213464	NCBI Gene Model | MGI Sequence Detail	28299	C57BL/6J
transcript	NM_172517	RefSeq | MGI Sequence Detail	3632	C57BL/6
polypeptide	Q8BX09	UniProt | EBI | MGI Sequence Detail	538	Not Applicable

All sequences(42) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(155 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001680	WD40 repeat
InterPro	IPR017986	WD40-repeat-containing domain
InterPro	IPR015943	WD40/YVTN repeat-like-containing domain
Protein Ontology	PR:000013777	retinoblastoma-binding protein 5

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193339 Yang YJ, et al., Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation. Cell. 2012 Nov 21;151(5):1097-112
All references(35)