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Rbbp5
Gene Detail
 Symbol
Name
ID
Rbbp5
retinoblastoma binding protein 5
MGI:1918367
Synonyms 4933411J24Rik
Feature Type protein coding gene
Genetic Map
Chromosome 1
57.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:132477365-132505659 bp, + strand
From VEGA annotation of GRCm38

  28295 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3709  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rbbp5

Human
homologs
Human Homolog RBBP5, retinoblastoma binding protein 5
NCBI Gene ID 5929
neXtProt AC  NX_Q15291
Human Synonyms  RBQ3, SWD1
Human Chr (Location)  1q32; chr1:205086142-205122022 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(57) : Gene trapped(57)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rbbp5 interacts with 294 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cellular response to DNA damage stimulus, chromatin modification, ...
Component histone methyltransferase complex, MLL1 complex, ...
Function histone methyltransferase activity (H3-K4 specific), methylated histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (24)    Tissues (15)    Images (2)
Theiler Stages: 23
Assay TypeResults
RNA in situ 24
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000049391 (Evidence)
Ensembl Gene ModelENSMUSG00000026439 (Evidence)
Entrez Gene213464 (Evidence)
DFCITC1579017, TC1583740, TC1698130, TC1762016
DoTSDT.101313945, DT.101383715, DT.110531116, DT.55280555, DT.97360570
NIA Mouse Gene IndexU000803, U338720
PDB2XL2, 2XL3
Consensus CDS ProjectCCDS15286.1
International Mouse Knockout Project StatusRbbp5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049391 VEGA Gene Model | MGI Sequence Detail 28295 C57BL/6J ±  kb
transcript OTTMUST00000125904 VEGA | MGI Sequence Detail 2856 Not Applicable 
polypeptide OTTMUSP00000068135 VEGA | MGI Sequence Detail 538 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(10) UniProt(2)
Polymorphisms SNPs within 2kb(196 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000013777 retinoblastoma-binding protein 5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204007 Ravnskjaer K, et al., Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013 Oct 1;123(10):4318-28
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory