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Rbbp5
Gene Detail
Symbol

Name
ID
Rbbp5
retinoblastoma binding protein 5
MGI:1918367
Synonyms
4933411J24Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
57.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:132477365-132505659 bp, + strand
From VEGA annotation of GRCm38

  28295 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3709  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RBBP5
Gene Tree: Rbbp5

Human
homologs
RBBP5, retinoblastoma binding protein 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 5929
neXtProt AC: NX_Q15291

Human Synonyms: RBQ3, SWD1

Human Chr (Location): 1q32; chr1:205086142-205122022 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(57) : Gene trapped(57)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Rbbp5 interacts with 294 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (25)    Tissues (16)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
Western blot 1
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rbbp5 ; ZFIN rbbp5    NEW 
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000049391 (Evidence)
Ensembl Gene Model ENSMUSG00000026439 (Evidence)
Entrez Gene 213464 (Evidence)
DFCI TC1698130, TC1583740, TC1579017, TC1762016
DoTS DT.101313945, DT.110531116, DT.101383715, DT.55280555, DT.97360570
NIA Mouse Gene Index U338720, U000803
PDB 2XL3, 2XL2
Consensus CDS Project CCDS15286.1
International Mouse Phenotyping Consortium Status Rbbp5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049391 VEGA Gene Model | MGI Sequence Detail 28295 C57BL/6J ±  kb
transcript OTTMUST00000125904 VEGA | MGI Sequence Detail 2856 Not Applicable 
polypeptide OTTMUSP00000068135 VEGA | MGI Sequence Detail 538 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(196 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000013777 retinoblastoma-binding protein 5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204007 Ravnskjaer K, et al., Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013 Oct 1;123(10):4318-28
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory