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Als2cr12 Gene Detail
Summary
  • Symbol
    Als2cr12
  • Name
    amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 (human)
  • Synonyms
    4933405P16Rik, 4933425F06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918359
    NCBI Gene: 108812
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr1:58646903-58695989 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      49087 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 29.15 cM, cytoband C2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ALS2CR12, amyotrophic lateral sclerosis 2 chromosome region 12
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ALS2CR12, amyotrophic lateral sclerosis 2 chromosome region 12
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 130540
    neXtProt AC: NX_Q96Q35
    UniProt: Q96Q35

  • Chr Location
    2q33.1; chr2:201288271-201357398 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047212 VEGA Gene Model | MGI Sequence Detail 49087 C57BL/6J ±  kb
transcript OTTMUST00000122081 VEGA | MGI Sequence Detail 1489 Not Applicable  
polypeptide OTTMUSP00000067066 VEGA | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    191 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003974 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein
  • InterPro Domains
    IPR026674 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:1921656
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:237827 Gineste C, et al., In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Neuromuscul Disord. 2013 Apr;23(4):357-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory