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Als2cr12 Gene Detail
Summary
  • Symbol
    Als2cr12
  • Name
    amyotrophic lateral sclerosis 2 chromosome region 12
  • Synonyms
    4933405P16Rik, 4933425F06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918359
    NCBI Gene: 108812
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:58656926-58696009 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 29.15 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918359
protein coding gene Chr1:58646903-58696009 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016056
protein coding gene Chr1:58557113-58841681 (-)
A/J MGP_AJ_G0016039
protein coding gene Chr1:56501922-56550025 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0015994
protein coding gene Chr1:56538153-56839109 (-)
C3H/HeJ MGP_C3HHeJ_G0015826
protein coding gene Chr1:58299483-58637683 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016447
protein coding gene Chr1:60908538-60949249 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0015408
protein coding gene Chr1:57510211-57556553 (+)
CBA/J MGP_CBAJ_G0015798
protein coding gene Chr1:62725796-63058589 (-)
DBA/2J MGP_DBA2J_G0015899
protein coding gene Chr1:55916242-56217695 (-)
FVB/NJ MGP_FVBNJ_G0015901
protein coding gene Chr1:55229919-55303658 (-)
LP/J MGP_LPJ_G0015971
protein coding gene Chr1:59443368-59721634 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015921
protein coding gene Chr1:65687567-65765902 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016494
protein coding gene Chr1:58011637-58285716 (-)
PWK/PhJ MGP_PWKPhJ_G0015196
protein coding gene Chr1:55324814-55552341 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014977
protein coding gene Chr1:57746030-57768104 (-)
WSB/EiJ MGP_WSBEiJ_G0015471
protein coding gene Chr1:57719293-57748980 (-)



Homology
more
  • Human Ortholog
    ALS2CR12, amyotrophic lateral sclerosis 2 chromosome region 12
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ALS2CR12, amyotrophic lateral sclerosis 2 chromosome region 12
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 130540
    neXtProt AC: NX_Q96Q35
    UniProt: Q96Q35

  • Chr Location
    2q33.1; chr2:201288271-201357398 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108812 NCBI Gene Model | MGI Sequence Detail 39084 C57BL/6J ±  kb
transcript NM_175370 RefSeq | MGI Sequence Detail 1575 C57BL/6  
polypeptide Q8BVM7 UniProt | EBI | MGI Sequence Detail 383 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR026674 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:1921656
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:237827 Gineste C, et al., In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Neuromuscul Disord. 2013 Apr;23(4):357-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory