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Hexim2
Gene Detail
 Symbol
Name
ID
Hexim2
hexamethylene bis-acetamide inducible 2
MGI:1918309
Synonyms 4933402L21Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
66.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:103132429-103139876 bp, + strand
From VEGA annotation of GRCm38

  7448 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16946  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Hexim2

Human
homologs
Human Homolog HEXIM2, hexamethylene bis-acetamide inducible 2
NCBI Gene ID 124790
neXtProt AC  NX_Q96MH2
Human Chr (Location)  17q21.31; chr17:45159335-45170039 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(21) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hexim2 interacts with 125 markers (Mir1b, Mir17, Mir20b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleus
Function cyclin-dependent protein serine/threonine kinase inhibitor activity, snRNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000002961 (Evidence)
Ensembl Gene ModelENSMUSG00000043372 (Evidence)
Entrez Gene71059 (Evidence)
UniGene273871
DFCITC1585699, TC1615561
DoTSDT.101253135, DT.110525118, DT.60104989
NIA Mouse Gene IndexU013412
Consensus CDS ProjectCCDS25514.1
International Mouse Knockout Project StatusHexim2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002961 VEGA Gene Model | MGI Sequence Detail 7448 C57BL/6J ±  kb
transcript OTTMUST00000006073 VEGA | MGI Sequence Detail 1910 Not Applicable 
polypeptide OTTMUSP00000002867 VEGA | MGI Sequence Detail 313 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(14) UniProt(4)
Polymorphisms SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024872 HEXIM
InterPro IPR024876 HEXIM2
Protein Ontology PR:000008527 protein HEXIM2
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:191206 Okamura D, et al., Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells. Genes Dev. 2012 Nov 15;26(22):2477-82
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory