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Phf6
Gene Detail
Symbol

Name
ID
Phf6
PHD finger protein 6
MGI:1918248
Synonyms
2700007B13Rik, 4931428F02Rik, mKIAA1823
Feature Type
protein coding gene
Genetic Map
Chromosome X
29.28 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:52912266-52956943 bp, + strand
From VEGA annotation of GRCm38

  44678 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12375  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PHF6
Gene Tree: Phf6

Human
homologs
PHF6, PHD finger protein 6
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 84295
neXtProt AC: NX_Q8IWS0

Human Synonyms: BFLS, BORJ, CENP-31

Human Chr (Location): Xq26.3; chrX:134373312-134428792 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PHF6

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(7) Targeted(3)
Incidental mutations (data from APF )
Interactions
Phf6 interacts with 430 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component chromosome, chromosome, centromeric region, ...
Function DNA binding, enzyme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (423)    Tissues (172)    Images (93)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 125
RNA in situ 266
Northern blot 24
Western blot 8
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase phf6    NEW 
Molecular
reagents
All nucleic(20) cDNA(20)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000017343 (Evidence)
Ensembl Gene Model ENSMUSG00000025626 (Evidence)
Entrez Gene 70998 (Evidence)
DFCI TC1578028, TC1582173, TC1588596, TC1655395
DoTS DT.101343880, DT.529049, DT.55131717, DT.94216177
NIA Mouse Gene Index U019855
Consensus CDS Project CCDS30127.1, CCDS72380.1
International Mouse Phenotyping Consortium Status Phf6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017343 VEGA Gene Model | MGI Sequence Detail 44678 C57BL/6J ±  kb
transcript OTTMUST00000042126 VEGA | MGI Sequence Detail 4350 Not Applicable 
polypeptide OTTMUSP00000018937 VEGA | MGI Sequence Detail 364 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(181 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001965 Zinc finger, PHD-type
Protein Ontology PR:000012653 PHD finger protein 6
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201693 Zhang C, et al., The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain. Neuron. 2013 Jun 19;78(6):986-93
All references(41)
Other
accession IDs
MGI:1919774

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory