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Psd3 Gene Detail
Summary
  • Symbol
    Psd3
  • Name
    pleckstrin and Sec7 domain containing 3
  • Synonyms
    4931420C21Rik, EFA6D, MGC:6957
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918215
    NCBI Gene: 234353
  • Gene Overview
    MyGene.info: PSD3
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:67689082-68206057 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 33.46 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2547 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918215
protein coding gene Chr8:67689082-68212027 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033659
protein coding gene Chr8:67796530-68179290 (-)
A/J MGP_AJ_G0033641
protein coding gene Chr8:65065411-65429161 (-)
AKR/J MGP_AKRJ_G0033566
protein coding gene Chr8:66807409-67198006 (-)
BALB/cJ MGP_BALBcJ_G0033637
protein coding gene Chr8:65238465-65614680 (-)
C3H/HeJ MGP_C3HHeJ_G0033347
protein coding gene Chr8:67552024-67926536 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034154
protein coding gene Chr8:70346381-70733204 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031101
protein coding gene Chr8:59979788-60339511 (-)
CAST/EiJ MGP_CASTEiJ_G0032672
protein coding gene Chr8:66987648-67380132 (-)
CBA/J MGP_CBAJ_G0033325
protein coding gene Chr8:72990009-73400338 (-)
DBA/2J MGP_DBA2J_G0033479
protein coding gene Chr8:64761628-65135373 (-)
FVB/NJ MGP_FVBNJ_G0033420
protein coding gene Chr8:63942524-64310729 (-)
LP/J MGP_LPJ_G0033567
protein coding gene Chr8:67890384-68268280 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033464
protein coding gene Chr8:75629773-76059151 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034172
protein coding gene Chr8:67108275-67482739 (-)
PWK/PhJ MGP_PWKPhJ_G0032381
protein coding gene Chr8:64025858-64391044 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032217
protein coding gene Chr8:66013771-66393564 (-)
WSB/EiJ MGP_WSBEiJ_G0032789
protein coding gene Chr8:67480888-67850092 (-)



Homology
more
  • Human Ortholog
    PSD3, pleckstrin and Sec7 domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSD3, pleckstrin and Sec7 domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EFA6D, EFA6R, HCA67
  • Links
    NCBI Gene ID: 23362
    neXtProt AC: NX_Q9NYI0
    UniProt: Q9NYI0

  • Chr Location
    8p22; chr8:18527303-19086909 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 87257
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PSD3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 234353 NCBI Gene Model | MGI Sequence Detail 516976 C57BL/6J ±  kb
transcript NM_177698 RefSeq | MGI Sequence Detail 11334 C57BL/6  
polypeptide Q2PFD7 UniProt | EBI | MGI Sequence Detail 1037 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    Genomic 2
    cDNA 72
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1933127, MGI:2142608
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:234999 Fukaya M, et al., Distinct subcellular localization of alternative splicing variants of EFA6D, a guanine nucleotide exchange factor for Arf6, in the mouse brain. J Comp Neurol. 2016 Sep 1;524(13):2531-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory