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Trim45
Gene Detail
Symbol

Name
ID
Trim45
tripartite motif-containing 45
MGI:1918187
Synonyms
4921530N01Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
43.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:100922202-100936920 bp, + strand
From VEGA annotation of GRCm38

  14719 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: TRIM45
Gene Tree: Trim45

Human
homologs
TRIM45, tripartite motif containing 45
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 80263
neXtProt AC: NX_Q9H8W5

Human Synonyms: RNF99

Human Chr (Location): 1p13.1; chr1:117111055-117121789 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Trim45 interacts with 294 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process bone development
Component cytoplasm, intercellular bridge, ...
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (69)    Tissues (34)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 69
cDNA source data(21)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase trim45    NEW 
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000007079 (Evidence)
Ensembl Gene Model ENSMUSG00000033233 (Evidence)
Entrez Gene 229644 (Evidence)
UniGene 189351
DFCI TC1585101, TC1598194, TC1675856
DoTS DT.101372535, DT.55171067, DT.94230456, DT.99856384
NIA Mouse Gene Index U042464
Consensus CDS Project CCDS17678.1, CCDS51018.1
International Mouse Phenotyping Consortium Status Trim45
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007079 VEGA Gene Model | MGI Sequence Detail 14719 C57BL/6J ±  kb
transcript OTTMUST00000016377 VEGA | MGI Sequence Detail 2274 Not Applicable 
polypeptide OTTMUSP00000007492 VEGA | MGI Sequence Detail 757 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(10) UniProt(3)
Polymorphisms
SNPs within 2kb(76 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003649 B-box, C-terminal
InterPro IPR000315 B-box-type zinc finger
InterPro IPR001298 Filamin/ABP280 repeat
InterPro IPR017868 Filamin/ABP280 repeat-like
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR018957 Zinc finger, C3HC4 RING-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000016659 tripartite motif-containing protein 45
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:188142 Bassett JH, et al., Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. PLoS Genet. 2012 Aug;8(8):e1002858
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory