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Nsun7
Gene Detail
Symbol

Name
ID
Nsun7
NOL1/NOP2/Sun domain family, member 7
MGI:1918168
Synonyms
4921525L17Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
34.34 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:66259912-66298016 bp, + strand
From VEGA annotation of GRCm38

  38105 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11653  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Nsun7

Human
homologs
Human Homolog NSUN7, NOP2/Sun domain family, member 7
NCBI Gene ID 79730
neXtProt AC  NX_Q8NE18
Human Chr (Location)  4p14; chr4:40749897-40809985 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Chemically induced (ENU)(1) Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Males homozygous for an ENU-induced mutation are either infertile or subfertile. Mutant sperm exhibit poor progressive motility linked to rigidity of the flagellar midpiece and abnormal electron density patterns in the mitochondrial sheath.
 
Interactions
Nsun7 interacts with 167 markers (Mir15a, Mir16-1, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (68 annotations)
Process methylation
Function 1-hydroxy-6-methoxypyrene methyltransferase activity, 1-hydroxypyrene methyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (42)    Tissues (5)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 42
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000024413 (Evidence)
Ensembl Gene ModelENSMUSG00000029206 (Evidence)
Entrez Gene70918 (Evidence)
DFCITC1666328, TC1689703, TC1588243, TC1592340
DoTSDT.101196963, DT.40178549, DT.50316150, DT.55183784, DT.55233916, DT.94294477
NIA Mouse Gene IndexU040639
EC2.1.1.-
Consensus CDS ProjectCCDS19314.1
International Mouse Knockout Project StatusNsun7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024413 VEGA Gene Model | MGI Sequence Detail 38105 C57BL/6J ±  kb
transcript OTTMUST00000059845 VEGA | MGI Sequence Detail 2346 Not Applicable 
polypeptide OTTMUSP00000029148 VEGA | MGI Sequence Detail 705 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(20) UniProt(7)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001678 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p
Protein Ontology PR:000031628 methyltransferase NSUN7
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203014 Chi L, et al., Expression of NOL1/NOP2/sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis. Gene Expr Patterns. 2013 Dec;13(8):319-27
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory