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Efcab3 Gene Detail
Summary
  • Symbol
    Efcab3
  • Name
    EF-hand calcium binding domain 3
  • Synonyms
    4921510J17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918144
    NCBI Gene: 70894
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:105063592-105117537 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.61 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1827 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918144
protein coding gene Chr11:105008985-105117537 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019280
protein coding gene Chr11:108126610-108326806 (+)
A/J MGP_AJ_G0019248
protein coding gene Chr11:103502531-103695825 (+)
AKR/J MGP_AKRJ_G0019217
protein coding gene Chr11:106658381-106845839 (+)
BALB/cJ MGP_BALBcJ_G0019222
protein coding gene Chr11:103941423-104135849 (+)
C3H/HeJ MGP_C3HHeJ_G0019031
protein coding gene Chr11:107069575-107129295 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019672
protein coding gene Chr11:111624394-111684594 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017297
protein coding gene Chr11:100867476-101055177 (+)
CAST/EiJ MGP_CASTEiJ_G0018585
protein coding gene Chr11:107964539-108174641 (+)
CBA/J MGP_CBAJ_G0019000
protein coding gene Chr11:116245943-116317709 (+)
DBA/2J MGP_DBA2J_G0019112
protein coding gene Chr11:103010667-103204866 (+)
FVB/NJ MGP_FVBNJ_G0019103
protein coding gene Chr11:102662252-102715074 (+)
LP/J MGP_LPJ_G0019182
protein coding gene Chr11:108585814-108794282 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019133
protein coding gene Chr11:115542597-115602150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019709
protein coding gene Chr11:107255218-107317181 (+)
PWK/PhJ MGP_PWKPhJ_G0018350
protein coding gene Chr11:104096983-104293085 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018140
protein coding gene Chr11:106870954-107066130 (+)
WSB/EiJ MGP_WSBEiJ_G0018635
protein coding gene Chr11:107083747-107284362 (+)



Homology
more
  • Human Ortholog
    EFCAB3, EF-hand calcium binding domain 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    EFCAB3, EF-hand calcium binding domain 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 146779
    neXtProt AC: NX_Q8N7B9
    UniProt: Q8N7B9

  • Chr Location
    17q23.2; chr17:62370218-62416479 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020690 Ensembl Gene Model | MGI Sequence Detail 53946 C57BL/6J ±  kb
transcript ENSMUST00000021029 Ensembl | MGI Sequence Detail 1757 Not Applicable  
polypeptide ENSMUSP00000021029 Ensembl | MGI Sequence Detail 432 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory