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Efcab3 Gene Detail
Summary
  • Symbol
    Efcab3
  • Name
    EF-hand calcium binding domain 3
  • Synonyms
    4921510J17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918144
    NCBI Gene: 70894
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:105063592-105117537 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.61 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1827 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918144
protein coding gene Chr11:105008985-105117537 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019280
protein coding gene Chr11:108126610-108326806 (+)
A/J MGP_AJ_G0019248
protein coding gene Chr11:103502531-103695825 (+)
AKR/J MGP_AKRJ_G0019217
protein coding gene Chr11:106658381-106845839 (+)
BALB/cJ MGP_BALBcJ_G0019222
protein coding gene Chr11:103941423-104135849 (+)
C3H/HeJ MGP_C3HHeJ_G0019031
protein coding gene Chr11:107069575-107129295 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019672
protein coding gene Chr11:111624394-111684594 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017297
protein coding gene Chr11:100867476-101055177 (+)
CAST/EiJ MGP_CASTEiJ_G0018585
protein coding gene Chr11:107964539-108174641 (+)
CBA/J MGP_CBAJ_G0019000
protein coding gene Chr11:116245943-116317709 (+)
DBA/2J MGP_DBA2J_G0019112
protein coding gene Chr11:103010667-103204866 (+)
FVB/NJ MGP_FVBNJ_G0019103
protein coding gene Chr11:102662252-102715074 (+)
LP/J MGP_LPJ_G0019182
protein coding gene Chr11:108585814-108794282 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019133
protein coding gene Chr11:115542597-115602150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019709
protein coding gene Chr11:107255218-107317181 (+)
PWK/PhJ MGP_PWKPhJ_G0018350
protein coding gene Chr11:104096983-104293085 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018140
protein coding gene Chr11:106870954-107066130 (+)
WSB/EiJ MGP_WSBEiJ_G0018635
protein coding gene Chr11:107083747-107284362 (+)



Homology
more
  • Human Ortholog
    EFCAB3, EF-hand calcium binding domain 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    EFCAB3, EF-hand calcium binding domain 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 146779
    neXtProt AC: NX_Q8N7B9
    UniProt: Q8N7B9

  • Chr Location
    17q23.2; chr17:62370218-62416479 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020690 Ensembl Gene Model | MGI Sequence Detail 53946 C57BL/6J ±  kb
    transcript ENSMUST00000021029 Ensembl | MGI Sequence Detail 1757 Not Applicable  
    polypeptide ENSMUSP00000021029 Ensembl | MGI Sequence Detail 432 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    References
    more
    • Summaries
      All 27
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:267883 Lilue J, et al., Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci. Nat Genet. 2018 Nov;50(11):1574-1583

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    05/26/2020
    MGI 6.15
    The Jackson Laboratory