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Spata16 Gene Detail
Summary
  • Symbol
    Spata16
  • Name
    spermatogenesis associated 16
  • Synonyms
    4921511F01Rik, 4930503K02Rik, Nyd-sp12, spermatogenesis-related protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918112
    NCBI Gene: 70862
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:26637620-26983212 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 10.74 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2275 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918112
protein coding gene Chr3:26637620-26983212 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027107
protein coding gene Chr3:23935857-24286929 (+)
A/J MGP_AJ_G0027067
protein coding gene Chr3:23785461-24124964 (+)
AKR/J MGP_AKRJ_G0027036
protein coding gene Chr3:24073261-24413336 (+)
BALB/cJ MGP_BALBcJ_G0027079
protein coding gene Chr3:23459111-23791454 (+)
C3H/HeJ MGP_C3HHeJ_G0026820
protein coding gene Chr3:24093709-24458776 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027524
protein coding gene Chr3:25275958-25636595 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024886
protein coding gene Chr3:21839583-22145771 (+)
CAST/EiJ MGP_CASTEiJ_G0026275
protein coding gene Chr3:23933015-24284929 (+)
CBA/J MGP_CBAJ_G0026798
protein coding gene Chr3:25915397-26293822 (+)
DBA/2J MGP_DBA2J_G0026932
protein coding gene Chr3:23335867-23671581 (+)
FVB/NJ MGP_FVBNJ_G0026900
protein coding gene Chr3:22821350-23149334 (+)
LP/J MGP_LPJ_G0027044
protein coding gene Chr3:24622280-24967067 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026921
protein coding gene Chr3:28546821-28914421 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027584
protein coding gene Chr3:23772120-24130534 (+)
PWK/PhJ MGP_PWKPhJ_G0026008
protein coding gene Chr3:22812787-23133446 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025818
protein coding gene Chr3:23351957-23691162 (+)
WSB/EiJ MGP_WSBEiJ_G0026348
protein coding gene Chr3:23824711-24166898 (+)



Homology
more
  • Human Ortholog
    SPATA16, spermatogenesis associated 16
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SPATA16, spermatogenesis associated 16
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NYD-SP12, SPGF6
  • Links
    NCBI Gene ID: 83893
    neXtProt AC: NX_Q9BXB7
    UniProt: Q9BXB7

  • Chr Location
    3q26.31; chr3:172889357-173141268 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Spata16 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 2 alleles in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a deletion of the fourth exon exhibit male infertility mice due to spermiogenic arrest but not globozoospermia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70862 NCBI Gene Model | MGI Sequence Detail 345593 C57BL/6J ±  kb
transcript NM_029150 RefSeq | MGI Sequence Detail 2011 C57BL/6  
polypeptide Q8C636 UniProt | EBI | MGI Sequence Detail 571 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922288
References
more
  • Summaries
    All 27
    Diseases 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:258202 Fujihara Y, et al., Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models. Int J Mol Sci. 2017 Oct 21;18(10)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory