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Sept10 Gene Detail
Summary
  • Symbol
    Sept10
  • Name
    septin 10
  • Synonyms
    4921515A04Rik, 9430099J10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918110
    NCBI Gene: 103080
Location & Maps
more
  • Sequence Map
    Chr10:59164113-59221847 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      57735 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SEPT10, septin 10
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SEPT10, septin 10
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 151011
    neXtProt AC: NX_Q9P0V9

  • Chr Location
    2q13; chr2:109542797-109614206 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Sept10
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019917 Ensembl Gene Model | MGI Sequence Detail 57735 C57BL/6J ±  kb
transcript ENSMUST00000165971 Ensembl | MGI Sequence Detail 2539 Not Applicable  
polypeptide ENSMUSP00000129023 Ensembl | MGI Sequence Detail 427 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    376 from dbSNP Build 137
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR016491 Septin
    IPR030379 Septin-type guanine nucleotide-binding (G) domain
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143466, MGI:2143700
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory