Prss22
Gene Detail

Symbol Name ID

Prss22 protease, serine, 22 MGI:1918085

Synonyms

4733401N09Rik, BSSP-4, SP001LA

Feature Type

protein coding gene

Genetic Map

Chromosome 17

12.18 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:23993535-23998100 bp, - strand From Ensembl annotation of GRCm38   4566 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:23344  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Prss22

Human homologs

Human Homolog		PRSS22, protease, serine, 22
NCBI Gene ID		64063
neXtProt AC		NX_Q9GZN4
Human Synonyms		BSSP-4, hBSSP-4
Human Chr (Location)		16p13.3; chr16:2902728-2908171 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	proteolysis
Component	cellular_component
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (20)    Tissues (20)    Images (1)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
RT-PCR	20

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000045027 (Evidence)
Entrez Gene	70835 (Evidence)
UniGene	157351
DFCI	TC1591668, TC1736296
DoTS	DT.55253606
NIA Mouse Gene Index	U065892
EC	3.4.21.-
Consensus CDS Project	CCDS37482.1
International Mouse Knockout Project Status	Prss22

Sequences

Length	Strain/Species
genomic	ENSMUSG00000045027	Ensembl Gene Model | MGI Sequence Detail	4566	C57BL/6J
transcript	ENSMUST00000041649	Ensembl | MGI Sequence Detail	1323	Not Applicable
polypeptide	ENSMUSP00000039808	Ensembl | MGI Sequence Detail	307	Not Applicable

All sequences(16) RefSeq(2) UniProt(2)

Polymorphisms

SNPs within 2kb(84 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000013322	brain-specific serine protease 4

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All references(24)