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Prss22 Gene Detail
Summary
  • Symbol
    Prss22
  • Name
    protease, serine 22
  • Synonyms
    4733401N09Rik, BSSP-4, SP001LA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918085
    NCBI Gene: 70835
  • Gene Overview
    MyGene.info: PRSS22
Location & Maps
more
  • Sequence Map
    Chr17:23993535-23998100 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4566 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.18 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PRSS22, protease, serine 22
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PRSS22, protease, serine 22
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BSSP-4, hBSSP-4, SP001LA
  • Links
    NCBI Gene ID: 64063
    neXtProt AC: NX_Q9GZN4

  • Chr Location
    16p13.3; chr16:2852727-2858630 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045027 Ensembl Gene Model | MGI Sequence Detail 4566 C57BL/6J ±  kb
transcript ENSMUST00000041649 Ensembl | MGI Sequence Detail 1323 Not Applicable  
polypeptide ENSMUSP00000039808 Ensembl | MGI Sequence Detail 307 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    121 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory