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Hmgxb4 Gene Detail
Summary
  • Symbol
    Hmgxb4
  • Name
    HMG box domain containing 4
  • Synonyms
    4733401K04Rik, Hmgb2l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918073
    NCBI Gene: 70823
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:74993518-75031978 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 35.57 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918073
protein coding gene Chr8:74993356-75031978 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033793
protein coding gene Chr8:75435994-75481481 (+)
A/J MGP_AJ_G0033775
protein coding gene Chr8:72477482-72517128 (+)
AKR/J MGP_AKRJ_G0033702
protein coding gene Chr8:74683524-74725870 (+)
BALB/cJ MGP_BALBcJ_G0033769
protein coding gene Chr8:72571267-72613742 (+)
C3H/HeJ MGP_C3HHeJ_G0033478
protein coding gene Chr8:75238345-75283808 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034289
protein coding gene Chr8:78366441-78407734 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031230
protein coding gene Chr8:66746318-66787244 (+)
CAST/EiJ MGP_CASTEiJ_G0032807
protein coding gene Chr8:74522143-74560044 (+)
CBA/J MGP_CBAJ_G0033457
protein coding gene Chr8:81119745-81162328 (+)
DBA/2J MGP_DBA2J_G0033611
protein coding gene Chr8:72159306-72204651 (+)
FVB/NJ MGP_FVBNJ_G0033556
protein coding gene Chr8:71243013-71281649 (+)
LP/J MGP_LPJ_G0033700
protein coding gene Chr8:75567876-75608703 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033599
protein coding gene Chr8:83682072-83724039 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034306
protein coding gene Chr8:74652406-74691614 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0032351
protein coding gene Chr8:73535215-73582175 (+)
WSB/EiJ MGP_WSBEiJ_G0032922
protein coding gene Chr8:74958678-74997837 (+)



Homology
more
  • Human Ortholog
    HMGXB4, HMG-box containing 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HMGXB4, HMG-box containing 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HMG2L1, HMGBCG, THC211630
  • Links
    NCBI Gene ID: 10042
    neXtProt AC: NX_Q9UGU5
    UniProt: Q9UGU5

  • Chr Location
    22q12.3; chr22:35257274-35295807 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70823 NCBI Gene Model | MGI Sequence Detail 38461 C57BL/6J ±  kb
transcript NM_001316753 RefSeq | MGI Sequence Detail 4035 C57BL/6  
polypeptide NP_821136 RefSeq | MGI Sequence Detail 594 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • InterPro Domains
    IPR025228 Domain of unknown function DUF4171
    IPR009071 High mobility group box domain
    IPR036910 High mobility group box domain superfamily
Molecular
Reagents
less
  • All nucleic 103
    Genomic 1
    cDNA 101
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142500
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory