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Rpusd2 Gene Detail
Summary
  • Symbol
    Rpusd2
  • Name
    RNA pseudouridylate synthase domain containing 2
  • Synonyms
    4921503C21Rik, BB231107
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918066
    NCBI Gene: 271842
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:119034790-119039769 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918066
protein coding gene Chr2:119034790-119042198 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026329
protein coding gene Chr2:121762928-121767898 (+)
A/J MGP_AJ_G0026290
protein coding gene Chr2:116806692-116811668 (+)
AKR/J MGP_AKRJ_G0026269
protein coding gene Chr2:120077659-120082635 (+)
BALB/cJ MGP_BALBcJ_G0026303
protein coding gene Chr2:117071579-117076549 (+)
C3H/HeJ MGP_C3HHeJ_G0026049
protein coding gene Chr2:120546329-120551304 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026750
protein coding gene Chr2:125759752-125764731 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024130
protein coding gene Chr2:111859578-111864585 (+)
CAST/EiJ MGP_CASTEiJ_G0025511
protein coding gene Chr2:120849443-120854412 (+)
CBA/J MGP_CBAJ_G0026025
protein coding gene Chr2:130190142-130195120 (+)
DBA/2J MGP_DBA2J_G0026164
protein coding gene Chr2:116235616-116240592 (+)
FVB/NJ MGP_FVBNJ_G0026126
protein coding gene Chr2:115053961-115058938 (+)
LP/J MGP_LPJ_G0026265
protein coding gene Chr2:122077258-122082225 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026145
protein coding gene Chr2:134557577-134562385 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026805
protein coding gene Chr2:120202853-120207826 (+)
PWK/PhJ MGP_PWKPhJ_G0025247
protein coding gene Chr2:115788309-115793307 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025046
protein coding gene Chr2:119384364-119389338 (+)
WSB/EiJ MGP_WSBEiJ_G0025580
protein coding gene Chr2:121031360-121036336 (+)



Homology
more
  • Human Ortholog
    RPUSD2, RNA pseudouridine synthase domain containing 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RPUSD2, RNA pseudouridine synthase domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C15orf19, C18B11, PUS9
  • Links
    NCBI Gene ID: 27079
    neXtProt AC: NX_Q8IZ73
    UniProt: Q8IZ73

  • Chr Location
    15q15.1; chr15:40569293-40574706 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027324 Ensembl Gene Model | MGI Sequence Detail 4980 C57BL/6J ±  kb
    transcript ENSMUST00000028796 Ensembl | MGI Sequence Detail 2706 Not Applicable  
    polypeptide ENSMUSP00000028796 Ensembl | MGI Sequence Detail 553 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000032511 RNA pseudouridylate synthase domain-containing protein 2
    • InterPro Domains
      IPR020103 Pseudouridine synthase, catalytic domain superfamily
      IPR006225 Pseudouridine synthase, RluC/RluD
      IPR006224 Pseudouridine synthase, RluC/RluD, conserved site
      IPR006145 Pseudouridine synthase, RsuA/RluA
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 29

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3034585
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    05/14/2019
    MGI 6.14
    The Jackson Laboratory