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Hars2
Gene Detail
 Symbol
Name
ID
Hars2
histidyl-tRNA synthetase 2, mitochondrial (putative)
MGI:1918041
Synonyms 4631412B19Rik, Harsl, HARSR, HO3
Feature Type protein coding gene
Genetic Map
Chromosome 18
19.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:36783008-36792562 bp, + strand
From VEGA annotation of GRCm38

  9555 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40819  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: histidyl-tRNA synthetase
Gene Tree: Hars2

Human
homologs
Human Homolog HARS2, histidyl-tRNA synthetase 2, mitochondrial
NCBI Gene ID 23438
neXtProt AC  NX_P49590
Human Synonyms  HARSL, HARSR, HO3, PRLTS2
Human Chr (Location)  5q31.3; chr5:140691426-140699318 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human HARS2
Alleles
and
phenotypes
All alleles(3) : Gene trapped(3)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process histidyl-tRNA aminoacylation, translation, ...
Component cytoplasm, mitochondrion
Function aminoacyl-tRNA ligase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (96)    Tissues (96)    Images (1)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 96
cDNA source data(56)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(56) cDNA(56)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000033867 (Evidence)
Ensembl Gene ModelENSMUSG00000019143 (Evidence)
Entrez Gene70791 (Evidence)
UniGene282700
DFCITC1577372, TC1649981
DoTSDT.533074, DT.91292827, DT.99852407
NIA Mouse Gene IndexU018596
EC6.1.1.21
Consensus CDS ProjectCCDS29165.1
International Mouse Knockout Project StatusHars2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033867 VEGA Gene Model | MGI Sequence Detail 9555 C57BL/6J ±  kb
transcript OTTMUST00000085354 VEGA | MGI Sequence Detail 3336 Not Applicable 
polypeptide OTTMUSP00000046108 VEGA | MGI Sequence Detail 505 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(9) UniProt(4)
Polymorphisms SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006195 Aminoacyl-tRNA synthetase, class II
InterPro IPR004154 Anticodon-binding
InterPro IPR015807 Histidine-tRNA ligase
InterPro IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
Protein Ontology PR:000029775 histidine--tRNA ligase, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2147244

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory