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Rasgef1a Gene Detail
Summary
  • Symbol
    Rasgef1a
  • Name
    RasGEF domain family, member 1A
  • Synonyms
    6330404M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917977
    NCBI Gene: 70727
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:118011475-118091546 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 55.85 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    386 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917977
protein coding gene Chr6:118011438-118091546 (.)
129S1/SvImJ MGP_129S1SvImJ_G0031182
protein coding gene Chr6:120742391-120830497 (+)
A/J MGP_AJ_G0031151
protein coding gene Chr6:116121567-116202203 (+)
AKR/J MGP_AKRJ_G0031082
protein coding gene Chr6:119243007-119331929 (+)
BALB/cJ MGP_BALBcJ_G0031162
protein coding gene Chr6:115898659-115981181 (+)
C3H/HeJ MGP_C3HHeJ_G0030547
protein coding gene Chr6:64963384-65047778 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031620
protein coding gene Chr6:123920175-123945283 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028782
protein coding gene Chr6:113049603-113131730 (+)
CAST/EiJ MGP_CASTEiJ_G0030269
protein coding gene Chr6:119616936-119710537 (+)
CBA/J MGP_CBAJ_G0030845
protein coding gene Chr6:128804476-128829561 (+)
DBA/2J MGP_DBA2J_G0031001
protein coding gene Chr6:115020785-115106288 (+)
FVB/NJ MGP_FVBNJ_G0030953
protein coding gene Chr6:114152787-114237835 (+)
LP/J MGP_LPJ_G0031080
protein coding gene Chr6:120770439-120859029 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030987
protein coding gene Chr6:132909389-132934347 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031649
protein coding gene Chr6:119331689-119357889 (+)
PWK/PhJ MGP_PWKPhJ_G0029984
protein coding gene Chr6:114031005-114120834 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029813
protein coding gene Chr6:117992978-118081229 (+)
WSB/EiJ MGP_WSBEiJ_G0030352
protein coding gene Chr6:119598578-119625477 (+)



Homology
more
  • Human Ortholog
    RASGEF1A, RasGEF domain family member 1A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RASGEF1A, RasGEF domain family member 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CG4853
  • Links
    NCBI Gene ID: 221002
    neXtProt AC: NX_Q8N9B8
    UniProt: Q8N9B8

  • Chr Location
    10q11.21; chr10:43194533-43266919 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70727 NCBI Gene Model | MGI Sequence Detail 80072 C57BL/6J ±  kb
transcript NM_001362105 RefSeq | MGI Sequence Detail 3379 C57BL/6  
polypeptide NP_001349032 RefSeq | MGI Sequence Detail 498 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily
    IPR023578 Ras guanine nucleotide exchange factor domain superfamily
    IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
    IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 6
Other
Accession IDs
less
MGI:2141473
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory