About   Help   FAQ
Med26 Gene Detail
Summary
  • Symbol
    Med26
  • Name
    mediator complex subunit 26
  • Synonyms
    5730493L18Rik, Crsp7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917875
    NCBI Gene: 70625
  • Gene Overview
    MyGene.info: MED26
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:72494561-72548270 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 35.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    244 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917875
protein coding gene Chr8:72494558-72548310 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033785
protein coding gene Chr8:72996707-73052729 (-)
A/J MGP_AJ_G0033767
protein coding gene Chr8:70028539-70084414 (-)
AKR/J MGP_AKRJ_G0033694
protein coding gene Chr8:72104180-72178308 (-)
BALB/cJ MGP_BALBcJ_G0033761
protein coding gene Chr8:70174333-70227622 (-)
C3H/HeJ MGP_C3HHeJ_G0033470
protein coding gene Chr8:72739468-72797438 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034281
protein coding gene Chr8:75764413-75824175 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031222
protein coding gene Chr8:64551762-64606593 (-)
CAST/EiJ MGP_CASTEiJ_G0032799
protein coding gene Chr8:72085760-72144211 (-)
CBA/J MGP_CBAJ_G0033449
protein coding gene Chr8:78473915-78533264 (-)
DBA/2J MGP_DBA2J_G0033603
protein coding gene Chr8:69779662-69834373 (-)
FVB/NJ MGP_FVBNJ_G0033548
protein coding gene Chr8:68858963-68912757 (-)
LP/J MGP_LPJ_G0033692
protein coding gene Chr8:73079291-73134112 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033592
protein coding gene Chr8:80955947-81011206 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034298
protein coding gene Chr8:72187268-72251631 (-)
PWK/PhJ MGP_PWKPhJ_G0032505
protein coding gene Chr8:69041617-69099044 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032343
protein coding gene Chr8:71112798-71168762 (-)
WSB/EiJ MGP_WSBEiJ_G0032914
protein coding gene Chr8:72484391-72541027 (-)



Homology
more
  • Human Ortholog
    MED26, mediator complex subunit 26
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MED26, mediator complex subunit 26
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CRSP7, CRSP70
  • Links
    NCBI Gene ID: 9441
    neXtProt AC: NX_O95402
    UniProt: O95402

  • Chr Location
    19p13.11; chr19:16574907-16628204 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045248 Ensembl Gene Model | MGI Sequence Detail 53710 C57BL/6J ±  kb
transcript ENSMUST00000058534 Ensembl | MGI Sequence Detail 2997 Not Applicable  
polypeptide ENSMUSP00000058697 Ensembl | MGI Sequence Detail 588 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010298 mediator of RNA polymerase II transcription subunit 26
  • InterPro Domains
    IPR031416 Mediator complex subunit 26, C-terminal domain
    IPR031417 Mediator complex subunit 26, middle domain
    IPR035441 TFIIS/LEDGF domain superfamily
    IPR003617 Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
    IPR017923 Transcription factor IIS, N-terminal
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142528, MGI:2142791
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:264970 Takahashi H, et al., MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex. Nat Commun. 2015 Jan 9;6:5941

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory