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Fbxo33 Gene Detail
Summary
  • Symbol
    Fbxo33
  • Name
    F-box protein 33
  • Synonyms
    5730501N20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917861
    NCBI Gene: 70611
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:59200655-59219725 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 26.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917861
protein coding gene Chr12:59200655-59220129 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019771
protein coding gene Chr12:58407563-58428683 (-)
A/J MGP_AJ_G0019730
protein coding gene Chr12:56280501-56303809 (-)
AKR/J MGP_AKRJ_G0019705
protein coding gene Chr12:58076790-58095967 (-)
BALB/cJ MGP_BALBcJ_G0019710
protein coding gene Chr12:56662215-56685867 (-)
C3H/HeJ MGP_C3HHeJ_G0019515
protein coding gene Chr12:58189636-58209047 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020162
protein coding gene Chr12:60129519-60150553 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017782
protein coding gene Chr12:54646771-54666256 (-)
CAST/EiJ MGP_CASTEiJ_G0019067
protein coding gene Chr12:53067703-53088886 (-)
CBA/J MGP_CBAJ_G0019484
protein coding gene Chr12:62340565-62359638 (-)
DBA/2J MGP_DBA2J_G0019600
protein coding gene Chr12:56199377-56218449 (-)
FVB/NJ MGP_FVBNJ_G0019588
protein coding gene Chr12:55470095-55489120 (-)
LP/J MGP_LPJ_G0019672
protein coding gene Chr12:58439865-58460344 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019626
protein coding gene Chr12:63931155-63952175 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020196
protein coding gene Chr12:57512331-57531395 (-)
PWK/PhJ MGP_PWKPhJ_G0018833
protein coding gene Chr12:50542682-50562954 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018627
protein coding gene Chr12:51913215-51932001 (-)
WSB/EiJ MGP_WSBEiJ_G0019118
protein coding gene Chr12:58079695-58098721 (-)



Homology
more
  • Human Ortholog
    FBXO33, F-box protein 33
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FBXO33, F-box protein 33
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BMND12, c14_5247, Fbx33
  • Links
    NCBI Gene ID: 254170
    neXtProt AC: NX_Q7Z6M2
    UniProt: Q7Z6M2

  • Chr Location
    14q21.1; chr14:39396373-39432500 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 16501
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FBXO33
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035329 Ensembl Gene Model | MGI Sequence Detail 19071 C57BL/6J ±  kb
    transcript ENSMUST00000043204 Ensembl | MGI Sequence Detail 3688 Not Applicable  
    polypeptide ENSMUSP00000035948 Ensembl | MGI Sequence Detail 562 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      cDNA 57
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144868
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:254234 Kweon SM, et al., Erasure of Tet-Oxidized 5-Methylcytosine by a SRAP Nuclease. Cell Rep. 2017 Oct 10;21(2):482-494

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory