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Ecd
Gene Detail
Symbol

Name
ID
Ecd
ecdysoneless homolog (Drosophila)
MGI:1917851
Synonyms
5730461K03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
11.51 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:20319859-20348121 bp, - strand
From NCBI annotation of GRCm38

  28263 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ECD
Gene Tree: Ecd

Human
homologs
ECD, ecdysoneless homolog (Drosophila)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 11319
neXtProt AC: NX_O95905

Human Synonyms: GCR2, HSGT1

Human Chr (Location): 10q22.3; chr10:73134524-73168095 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(10) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit lethality (no time point given).
 
Interactions
Ecd interacts with 119 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell proliferation, regulation of G1/S transition of mitotic cell cycle, ...
Component cytoplasm, nucleoplasm, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (30)    Tissues (21)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 30
cDNA source data(126)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ecd    NEW 
Molecular
reagents
All nucleic(128) cDNA(128)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000021810 (Evidence)
Entrez Gene 70601 (Evidence)
UniGene 35105
DFCI TC1575433, TC1592451, TC1607108, TC1637260
DoTS DT.87072396
NIA Mouse Gene Index U035272
Consensus CDS Project CCDS26842.1
International Mouse Phenotyping Consortium Status Ecd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 70601 NCBI Gene Model | MGI Sequence Detail 28263 C57BL/6J ±  kb
transcript NM_027475 RefSeq | MGI Sequence Detail 3125 C57BL/6 
polypeptide Q9CS74 UniProt | EBI | MGI Sequence Detail 641 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(105 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010770 SGT1
Protein Ontology PR:000006873 protein SGT1
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory