Ssfa2
Gene Detail

Symbol Name ID

Ssfa2 sperm specific antigen 2 MGI:1917849

Synonyms

CS1, CS-1, KRAP, mKIAA1927, SPAG13

Feature Type

protein coding gene

Genetic Map

Chromosome 2

47.58 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr2:79635352-79672966 bp, + strand From VEGA annotation of GRCm38   37615 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4912  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ssfa2

Human homologs

Human Homolog		SSFA2, sperm specific antigen 2
NCBI Gene ID		6744
neXtProt AC		NX_P28290
Human Synonyms		CS1, CS-1, KRAP, SPAG13
Human Chr (Location)		2q31.3; chr2:181891716-181930738 (+)  GRCh38

Mutations, alleles, and phenotypes

All mutations/alleles(8) : Gene trapped(4) Targeted(4)
Genomic Mutations involving Ssfa2 (2)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for a null mutation display decreased body weight, resistance to diet induced obesity, increased food intake, decreased adipose tissue mass, elevated metabolic rate, abnormal glucose homeostasis, and abnormal hormone levels.

 
Phenotype Images(2)

Interactions

Ssfa2 interacts with 283 markers (Mir1a-1, Mir1a-2, Mir1b, ...)

View All

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Component	cytoplasm, nucleus, ...
Function	actin binding, receptor binding

External Resources: FuncBase

Expression

cDNA source data(100)
External Resources: GEO   Expression Atlas

Molecular reagents

All nucleic(100) cDNA(100)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000013318 (Evidence)
Ensembl Gene Model	ENSMUSG00000027007 (Evidence)
Entrez Gene	70599 (Evidence)
UniGene	272881
DFCI	TC1576124, TC1638687, TC1702059
DoTS	DT.101378816, DT.110687992, DT.488801
NIA Mouse Gene Index	U001964
Consensus CDS Project	CCDS16170.1
International Mouse Knockout Project Status	Ssfa2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000013318	VEGA Gene Model | MGI Sequence Detail	37615	C57BL/6J
transcript	OTTMUST00000032211	VEGA | MGI Sequence Detail	5168	Not Applicable
polypeptide	OTTMUSP00000014318	VEGA | MGI Sequence Detail	1252	Not Applicable

All sequences(50) RefSeq(5) UniProt(4)

Polymorphisms

SNPs within 2kb(312 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR026648	Sperm-specific antigen 2
Protein Ontology	PR:000015652	sperm-specific antigen 2

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)