About   Help   FAQ
Itprid2 Gene Detail
Summary
  • Symbol
    Itprid2
  • Name
    ITPR interacting domain containing 2
  • Synonyms
    CS1, CS-1, KRAP, mKIAA1927, SPAG13, Ssfa2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917849
    NCBI Gene: 70599
  • Gene Overview
    MyGene.info: ITPRID2
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:79635352-79672966 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 47.58 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    309 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917849
 protein coding gene Chr2:79635260-79672966 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025879
 protein coding gene Chr2:80191667-80230530 (+)
A/J MGP_AJ_G0025856
 protein coding gene Chr2:77091355-77128919 (+)
AKR/J MGP_AKRJ_G0025825
 protein coding gene Chr2:79100597-79138117 (+)
BALB/cJ MGP_BALBcJ_G0025852
 protein coding gene Chr2:77215838-77253591 (+)
C3H/HeJ MGP_C3HHeJ_G0025611
 protein coding gene Chr2:79333154-79371554 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026298
 protein coding gene Chr2:82557776-82596487 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023701
 protein coding gene Chr2:74340629-74378582 (+)
CAST/EiJ MGP_CASTEiJ_G0025073
 protein coding gene Chr2:79756150-79796322 (+)
CBA/J MGP_CBAJ_G0025592
 protein coding gene Chr2:85519913-85562591 (+)
DBA/2J MGP_DBA2J_G0025723
 protein coding gene Chr2:76640199-76677304 (+)
FVB/NJ MGP_FVBNJ_G0025685
 protein coding gene Chr2:76007193-76044604 (+)
LP/J MGP_LPJ_G0025811
 protein coding gene Chr2:80031417-80068873 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025716
 protein coding gene Chr2:87380168-87424892 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026354
 protein coding gene Chr2:79276752-79319032 (+)
PWK/PhJ MGP_PWKPhJ_G0024816
 protein coding gene Chr2:76585934-76627833 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024622
 protein coding gene Chr2:79548063-79585550 (+)
WSB/EiJ MGP_WSBEiJ_G0025142
 protein coding gene Chr2:79902643-79940561 (+)



Homology
more
  • Human Ortholog
    ITPRID2, ITPR interacting domain containing 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ITPRID2, ITPR interacting domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CS1, CS-1, KRAP, SPAG13, SSFA2
  • Links
    NCBI Gene ID: 6744
    neXtProt AC: NX_P28290
    UniProt: P28290

  • Chr Location
    2q31.3; chr2:181891716-181930738 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotypes from 1 allele in 2 genetic backgrounds
    2 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display decreased body weight, resistance to diet induced obesity, increased food intake, decreased adipose tissue mass, elevated metabolic rate, abnormal glucose homeostasis, and abnormal hormone levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    100
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027007 Ensembl Gene Model | MGI Sequence Detail 37615 C57BL/6J ±  kb
transcript ENSMUST00000111785 Ensembl | MGI Sequence Detail 5168 Not Applicable  
polypeptide ENSMUSP00000107415 Ensembl | MGI Sequence Detail 1252 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 100
    cDNA 100

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory