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Pnrc1 Gene Detail
Summary
  • Symbol
    Pnrc1
  • Name
    proline-rich nuclear receptor coactivator 1
  • Synonyms
    5730463C12Rik, B4-2, Prol2, PRR2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917838
    NCBI Gene: 108767
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:33245423-33248787 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 14.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917838
 protein coding gene Chr4:33245423-33290163 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028122
 protein coding gene Chr4:30755261-30805033 (-)
A/J MGP_AJ_G0028080
 protein coding gene Chr4:29655647-29701191 (-)
AKR/J MGP_AKRJ_G0028043
 protein coding gene Chr4:30434038-30484364 (-)
BALB/cJ MGP_BALBcJ_G0028091
 protein coding gene Chr4:29913887-29960004 (-)
C3H/HeJ MGP_C3HHeJ_G0027820
 protein coding gene Chr4:30726322-30775608 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028533
 protein coding gene Chr4:31959983-32009348 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025874
 protein coding gene Chr4:27823834-27866936 (-)
CAST/EiJ MGP_CASTEiJ_G0027275
 protein coding gene Chr4:30503585-30548885 (-)
CBA/J MGP_CBAJ_G0027792
 protein coding gene Chr4:33000918-33067570 (-)
DBA/2J MGP_DBA2J_G0027936
 protein coding gene Chr4:29654617-29700041 (-)
FVB/NJ MGP_FVBNJ_G0027902
 protein coding gene Chr4:29086228-29131167 (-)
LP/J MGP_LPJ_G0028044
 protein coding gene Chr4:30840678-30887678 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027935
 protein coding gene Chr4:35568434-35617494 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028592
 protein coding gene Chr4:30435256-30487042 (-)
PWK/PhJ MGP_PWKPhJ_G0026994
 protein coding gene Chr4:29659850-29705984 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026823
 protein coding gene Chr4:30321289-30369174 (-)
WSB/EiJ MGP_WSBEiJ_G0027351
 protein coding gene Chr4:30441129-30487837 (-)



Homology
more
  • Human Ortholog
    PNRC1, proline rich nuclear receptor coactivator 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PNRC1, proline rich nuclear receptor coactivator 1
  • Synonyms
    B4-2, PNAS-145, PROL2, PRR2
  • Links
    NCBI Gene ID: 10957
    neXtProt AC: NX_Q12796
    UniProt: Q12796

  • Chr Location
    6q15; chr6:89080710-89085160 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    23
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    18
  • Targeted
    2
  • Genomic Mutations
    1 involving Pnrc1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    23 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    94
  • cDNA Data
    98
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108767 NCBI Gene Model | MGI Sequence Detail 3365 C57BL/6J ±  kb
transcript NM_001033225 RefSeq | MGI Sequence Detail 1940 C57BL/6  
polypeptide NP_001028397 RefSeq | MGI Sequence Detail 297 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR026780 Proline-rich nuclear receptor coactivator 1/2
Molecular
Reagents
less
  • All nucleic 100
    cDNA 98
    Primer pair 1
    Other 1

    Microarray probesets 7
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/09/2022
MGI 6.21 		The Jackson Laboratory