About   Help   FAQ
Cpsf7 Gene Detail
Summary
  • Symbol
    Cpsf7
  • Name
    cleavage and polyadenylation specific factor 7
  • Synonyms
    5730453I16Rik, C330017N18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917826
    NCBI Gene: 269061
  • Gene Overview
    MyGene.info: CPSF7
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10525244-10547735 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917826
protein coding gene Chr19:10525244-10547735 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024847
protein coding gene Chr19:7870522-7894362 (+)
A/J MGP_AJ_G0024815
protein coding gene Chr19:7333320-7356974 (+)
AKR/J MGP_AKRJ_G0024790
protein coding gene Chr19:7623171-7646957 (+)
BALB/cJ MGP_BALBcJ_G0024815
protein coding gene Chr19:7378282-7401348 (+)
C3H/HeJ MGP_C3HHeJ_G0024581
protein coding gene Chr19:7509973-7531999 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025263
protein coding gene Chr19:8228791-8253471 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022690
protein coding gene Chr19:7753365-7776865 (+)
CAST/EiJ MGP_CASTEiJ_G0024054
protein coding gene Chr19:7163767-7185554 (+)
CBA/J MGP_CBAJ_G0024555
protein coding gene Chr19:8271938-8296774 (+)
DBA/2J MGP_DBA2J_G0024682
protein coding gene Chr19:7345771-7368863 (+)
FVB/NJ MGP_FVBNJ_G0024649
protein coding gene Chr19:7389486-7410338 (+)
LP/J MGP_LPJ_G0024769
protein coding gene Chr19:7834937-7859424 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024676
protein coding gene Chr19:8164541-8201395 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025311
protein coding gene Chr19:7641441-7667478 (+)
PWK/PhJ MGP_PWKPhJ_G0023799
protein coding gene Chr19:6788288-6811484 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023604
protein coding gene Chr19:6822816-6845208 (+)
WSB/EiJ MGP_WSBEiJ_G0024116
protein coding gene Chr19:7525446-7548587 (+)



Homology
more
  • Human Ortholog
    CPSF7, cleavage and polyadenylation specific factor 7
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CPSF7, cleavage and polyadenylation specific factor 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CFIm59
  • Links
    NCBI Gene ID: 79869
    neXtProt AC: NX_Q8N684
    UniProt: Q8N684

  • Chr Location
    11q12.2; chr11:61402648-61429992 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 269061 NCBI Gene Model | MGI Sequence Detail 22492 C57BL/6J ±  kb
transcript NM_001362450 RefSeq | MGI Sequence Detail 3670 C57BL/6  
polypeptide Q8BTV2 UniProt | EBI | MGI Sequence Detail 471 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005834 cleavage and polyadenylation specificity factor subunit 7
  • InterPro Domains
    IPR034770 Cleavage and polyadenylation specificity factor subunit 7
    IPR034772 CPSF6/7 family
    IPR034773 CPSF7, RNA recognition motif
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1924447, MGI:2147625
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory