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Wdr36
Gene Detail
Symbol

Name
ID
Wdr36
WD repeat domain 36
MGI:1917819
Synonyms
5730444A13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 18
18.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:32837225-32866420 bp, + strand
From NCBI annotation of GRCm38

  29196 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6536  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: WDR36
Gene Tree: Wdr36

Human
homologs
WDR36, WD repeat domain 36
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 134430
neXtProt AC: NX_Q8NI36

Human Synonyms: GLC1G, TAWDRP, TA-WDRP, UTP21

Human Chr (Location): 5q22.1; chr5:111092172-111130502 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human WDR36

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous inactivation of this gene leads to complete embryonic lethality before implantation. In culture, homozygous mutant embryos fail to reach the blastocyst stage.
 
Interactions
Wdr36 interacts with 83 markers (Mir16-1, Mir16-2, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process regulation of axon extension, retina homeostasis, ...
Component nucleolus, Pwp2p-containing subcomplex of 90S preribosome, ...
Function poly(A) RNA binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (91)    Tissues (8)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 91
cDNA source data(123)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase wdr36    NEW 
Molecular
reagents
All nucleic(123) cDNA(123)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000038299 (Evidence)
Entrez Gene 225348 (Evidence)
UniGene 38816
DFCI TC1572446, TC1592230, TC1647799, TC1685261
NIA Mouse Gene Index U043655
Consensus CDS Project CCDS50245.1, CCDS50246.1
International Mouse Phenotyping Consortium Status Wdr36
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 225348 NCBI Gene Model | MGI Sequence Detail 29196 C57BL/6J ±  kb
transcript NM_001110015 RefSeq | MGI Sequence Detail 3281 C57BL/6 
polypeptide NP_001103485 RefSeq | MGI Sequence Detail 899 C57BL/6 

For the selected sequences
All sequences(51) RefSeq(8) UniProt(7)
Polymorphisms
SNPs within 2kb(192 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
InterPro IPR007319 Small-subunit processome, Utp21
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000017391 WD repeat-containing protein 36
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory