Lrfn2
Gene Detail

Symbol Name ID

Lrfn2 leucine rich repeat and fibronectin type III domain containing 2 MGI:1917780

Synonyms

5730420O05Rik, mKIAA1246, SALM1

Feature Type

protein coding gene

Genetic Map

Chromosome 17

24.66 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:48932379-49097588 bp, + strand From VEGA annotation of GRCm38   165210 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:19182  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Lrfn2

Human homologs

Human Homolog		LRFN2, leucine rich repeat and fibronectin type III domain containing 2
NCBI Gene ID		57497
neXtProt AC		NX_Q9ULH4
Human Synonyms		FIGLER2, KIAA1246, RP11-535K1.2, SALM1
Human Chr (Location)		6p21.2-p21.1; chr6:40359373-40555126 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(11) : Targeted(1) Gene trapped(9) Transgenic(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Component	cell junction, integral to membrane, ...
Function	protein binding

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (106)    Tissues (88)    Images (17)
Theiler Stages: 6, 8, 9, 11, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	71
Northern blot	35

cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(8) Primer pair(1) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000014931 (Evidence)
Ensembl Gene Model	ENSMUSG00000040490 (Evidence)
Entrez Gene	70530 (Evidence)
UniGene	133607
DFCI	TC1582911
DoTS	DT.55201748
NIA Mouse Gene Index	U018084
Consensus CDS Project	CCDS28871.1
International Mouse Knockout Project Status	Lrfn2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014931	VEGA Gene Model | MGI Sequence Detail	165210	C57BL/6J
transcript	OTTMUST00000035461	VEGA | MGI Sequence Detail	3202	Not Applicable
polypeptide	OTTMUSP00000015873	VEGA | MGI Sequence Detail	788	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(294 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000483	Cysteine-rich flanking region, C-terminal
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR013098	Immunoglobulin I-set
InterPro	IPR007110	Immunoglobulin-like domain
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003598	Immunoglobulin subtype 2
InterPro	IPR001611	Leucine-rich repeat
InterPro	IPR000372	Leucine-rich repeat-containing N-terminal
InterPro	IPR003591	Leucine-rich repeat, typical subtype
Protein Ontology	PR:000030703	leucine-rich repeat and fibronectin type-III domain-containing protein 2

References

(Earliest) J:126456 Badiani P, et al., Dominant interfering alleles define a role for c-Myb in T-cell development. Genes Dev. 1994 Apr 1;8(7):770-82
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)