Bbx
Gene Detail

Symbol Name ID

Bbx bobby sox homolog (Drosophila) MGI:1917758

Synonyms

5530401J07Rik, 5730403O13Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 16

31.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr16:50191844-50432390 bp, - strand From VEGA annotation of GRCm38   240547 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10634  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Bbx

Human homologs

Human Homolog		BBX, bobby sox homolog (Drosophila)
NCBI Gene ID		56987
neXtProt AC		NX_Q8WY36
Human Synonyms		ARTC1, HBP2, HSPC339, MDS001
Human Chr (Location)		3q13.1; chr3:107241783-107530050 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(52) : Targeted(2) Gene trapped(50)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	bone development, regulation of transcription, DNA-dependent, ...
Component	nucleus
Function	DNA binding

External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (142)    Tissues (69)    Images (25)
Theiler Stages: 2, 3, 4, 5, 17, 21, 23, 28

Assay Type	Results
RNA in situ	127
RT-PCR	15

cDNA source data(105)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(106) cDNA(105) Primer pair(1)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000017264 (Evidence)
Ensembl Gene Model	ENSMUSG00000022641 (Evidence)
Entrez Gene	70508 (Evidence)
UniGene	28940
DFCI	TC1579155, TC1584657, TC1587916, TC1600634, TC1603408, TC1612023, TC1631004
DoTS	DT.101138683, DT.101238979, DT.101264801, DT.101382737, DT.101382739, DT.40145858, DT.91279420, DT.94251217, DT.94251227, DT.97389003, DT.97394584, DT.99851224
NIA Mouse Gene Index	U037100, U363135
PDB	1WZ6
Consensus CDS Project	CCDS37354.1
International Mouse Knockout Project Status	Bbx

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017264	VEGA Gene Model | MGI Sequence Detail	240547	C57BL/6J
transcript	OTTMUST00000041776	VEGA | MGI Sequence Detail	8743	Not Applicable
polypeptide	OTTMUSP00000018781	VEGA | MGI Sequence Detail	907	Not Applicable

All sequences(91) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(1857 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009071	High mobility group (HMG) box domain
InterPro	IPR019102	HMG box transcription factor BBX, domain of unknown function DUF2028
Protein Ontology	PR:000004671	HMG box transcription factor BBX

References

(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:188142 Bassett JH, et al., Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. PLoS Genet. 2012 Aug;8(8):e1002858
All references(42)

Other accession IDs

MGI:1921753