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Arhgap17 Gene Detail
Summary
  • Symbol
    Arhgap17
  • Name
    Rho GTPase activating protein 17
  • Synonyms
    5730403H17Rik, Nadrin, Nadrin2, Rich1, WBP15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917747
    NCBI Gene: 70497
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:123279218-123369915 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 67.42 cM, cytoband F3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    665 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917747
protein coding gene Chr7:123279149-123370034 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032961
protein coding gene Chr7:127422788-127514833 (-)
A/J MGP_AJ_G0032944
protein coding gene Chr7:124110041-124202454 (-)
AKR/J MGP_AKRJ_G0032876
protein coding gene Chr7:127270213-127360624 (-)
BALB/cJ MGP_BALBcJ_G0032949
protein coding gene Chr7:123780424-123872749 (-)
C3H/HeJ MGP_C3HHeJ_G0032659
protein coding gene Chr7:127176958-127270219 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033455
protein coding gene Chr7:132388159-132480158 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030427
protein coding gene Chr7:125405272-125498336 (-)
CAST/EiJ MGP_CASTEiJ_G0031987
protein coding gene Chr7:118987027-119077787 (-)
CBA/J MGP_CBAJ_G0032632
protein coding gene Chr7:136853058-136945356 (-)
DBA/2J MGP_DBA2J_G0032784
protein coding gene Chr7:122093136-122184026 (-)
FVB/NJ MGP_FVBNJ_G0032737
protein coding gene Chr7:121943358-122035037 (-)
LP/J MGP_LPJ_G0032878
protein coding gene Chr7:128852665-128947141 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032769
protein coding gene Chr7:138195703-138288443 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033475
protein coding gene Chr7:126266751-126358439 (-)
PWK/PhJ MGP_PWKPhJ_G0031695
protein coding gene Chr7:115037862-115129132 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031541
protein coding gene Chr7:113041188-113132696 (-)
WSB/EiJ MGP_WSBEiJ_G0032100
protein coding gene Chr7:127176754-127268025 (-)



Homology
more
  • Human Ortholog
    ARHGAP17, Rho GTPase activating protein 17
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ARHGAP17, Rho GTPase activating protein 17
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH1, RICH-1, WBP15
  • Links
    NCBI Gene ID: 55114
    neXtProt AC: NX_Q68EM7
    UniProt: Q68EM7

  • Chr Location
    16p12.1; chr16:24919384-25015601 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030766 Ensembl Gene Model | MGI Sequence Detail 90698 C57BL/6J ±  kb
transcript ENSMUST00000106442 Ensembl | MGI Sequence Detail 3336 Not Applicable  
polypeptide ENSMUSP00000102050 Ensembl | MGI Sequence Detail 846 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 85
    cDNA 83
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:71028 Bedford MT, et al., A novel pro-Arg motif recognized by WW domains. J Biol Chem. 2000 Apr 7;275(14):10359-69
  • Latest
    J:239619 Rue L, et al., Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels. J Clin Invest. 2016 Nov 01;126(11):4319-4330

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory