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Snx21 Gene Detail
Summary
  • Symbol
    Snx21
  • Name
    sorting nexin family member 21
  • Synonyms
    5730407K14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917729
    NCBI Gene: 101113
  • Gene Overview
    MyGene.info: SNX21
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164785823-164793816 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.27 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917729
protein coding gene Chr2:164785768-164793816 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026873
protein coding gene Chr2:170286954-170294917 (+)
A/J MGP_AJ_G0026840
protein coding gene Chr2:163324376-163332373 (+)
AKR/J MGP_AKRJ_G0026811
protein coding gene Chr2:168178602-168186623 (+)
BALB/cJ MGP_BALBcJ_G0026849
protein coding gene Chr2:163683858-163691854 (+)
C3H/HeJ MGP_C3HHeJ_G0026591
protein coding gene Chr2:168542344-168550308 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027296
protein coding gene Chr2:175215736-175223714 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024667
protein coding gene Chr2:156730389-156738495 (+)
CAST/EiJ MGP_CASTEiJ_G0026049
protein coding gene Chr2:168959759-168967717 (+)
CBA/J MGP_CBAJ_G0026568
protein coding gene Chr2:181573567-181581524 (+)
DBA/2J MGP_DBA2J_G0026706
protein coding gene Chr2:162490094-162498060 (+)
FVB/NJ MGP_FVBNJ_G0026672
protein coding gene Chr2:160910496-160918456 (+)
LP/J MGP_LPJ_G0026808
protein coding gene Chr2:170346380-170354336 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026691
protein coding gene Chr2:185142299-185150283 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027353
protein coding gene Chr2:168085699-168093666 (+)
PWK/PhJ MGP_PWKPhJ_G0025786
protein coding gene Chr2:162090676-162098728 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025587
protein coding gene Chr2:166981808-166989842 (+)
WSB/EiJ MGP_WSBEiJ_G0026122
protein coding gene Chr2:168966725-168974715 (+)



Homology
more
  • Human Ortholog
    SNX21, sorting nexin family member 21
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNX21, sorting nexin family member 21
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf161, dJ337O18.4, PP3993, SNX-L
  • Links
    NCBI Gene ID: 90203
    neXtProt AC: NX_Q969T3
    UniProt: Q969T3

  • Chr Location
    20q13.12; chr20:45833418-45843275 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050373 Ensembl Gene Model | MGI Sequence Detail 7994 C57BL/6J ±  kb
transcript ENSMUST00000056181 Ensembl | MGI Sequence Detail 2590 Not Applicable  
polypeptide ENSMUSP00000054137 Ensembl | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141431
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:224694 Clairfeuille T, et al., Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21. J Biol Chem. 2015 Jun 5;290(23):14504-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory