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Cenpl Gene Detail
Summary
  • Symbol
    Cenpl
  • Name
    centromere protein L
  • Synonyms
    2610300B10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917704
    NCBI Gene: 70454
  • Gene Overview
    MyGene.info: CENPL
Location & Maps
more
  • Sequence Map
    Chr1:161070713-161086724 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16012 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CENPL, centromere protein L
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CENPL, centromere protein L
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C1orf155, CENP-L, dJ383J4.3
  • Links
    NCBI Gene ID: 91687
    neXtProt AC: NX_Q8N0S6

  • Chr Location
    1q25.1; chr1:173799550-173824639 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 19618
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CENPL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Gene trapped
    6
  • Targeted
    3
  • Genomic Mutations
    2 involving Cenpl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022157 VEGA Gene Model | MGI Sequence Detail 16012 C57BL/6J ±  kb
transcript OTTMUST00000052615 VEGA | MGI Sequence Detail 1910 Not Applicable  
polypeptide OTTMUSP00000024969 VEGA | MGI Sequence Detail 345 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    212 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000005332 centromere protein L
  • InterPro Domains
    IPR025204 Centromere subunit L
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138564, MGI:2138609
References
more
  • Summaries
    All 33
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory