Dhrs13 Gene Detail

Summary

• Symbol
  Dhrs13
• Name
  dehydrogenase/reductase (SDR family) member 13
• Synonyms
  2610209N15Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1917701
  NCBI Gene: 70451
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr11:78032313-78037864 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 46.74 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  1 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917701	protein coding gene	Chr11:78032280-78037866 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018760	protein coding gene	Chr11:78994268-78999854 (+)
A/J	MGP_AJ_G0018726	protein coding gene	Chr11:75987943-75993529 (+)
AKR/J	MGP_AKRJ_G0018696	protein coding gene	Chr11:78294297-78299883 (+)
BALB/cJ	MGP_BALBcJ_G0018700	protein coding gene	Chr11:76381934-76387520 (+)
C3H/HeJ	MGP_C3HHeJ_G0018513	protein coding gene	Chr11:78328397-78333983 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019151	protein coding gene	Chr11:81466625-81472211 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016786	protein coding gene	Chr11:72963165-72969803 (+)
CAST/EiJ	MGP_CASTEiJ_G0018067	protein coding gene	Chr11:78760638-78766146 (+)
CBA/J	MGP_CBAJ_G0018483	protein coding gene	Chr11:85019520-85025106 (+)
DBA/2J	MGP_DBA2J_G0018592	protein coding gene	Chr11:75570363-75575949 (+)
FVB/NJ	MGP_FVBNJ_G0018582	protein coding gene	Chr11:75152629-75158215 (+)
LP/J	MGP_LPJ_G0018663	protein coding gene	Chr11:79538476-79544062 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018608	protein coding gene	Chr11:85460945-85466531 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019191	protein coding gene	Chr11:78531180-78536766 (+)
PWK/PhJ	MGP_PWKPhJ_G0017838	protein coding gene	Chr11:76345672-76351245 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017629	protein coding gene	Chr11:78135017-78140611 (+)
WSB/EiJ	MGP_WSBEiJ_G0018120	protein coding gene	Chr11:78343422-78349012 (+)

Homology

• Human Ortholog
  DHRS13, dehydrogenase/reductase 13

• Vertebrate Orthologs
  14

• Human Ortholog
  DHRS13, dehydrogenase/reductase 13
  Orthology source: HomoloGene, HGNC
• Synonyms
  SDR7C5
• Links
  HGNC:28326

  NCBI Gene ID: 147015

  neXtProt AC: NX_Q6UX07

  UniProt: Q6UX07

  
  
• Chr Location
  17q11.2; chr17:28897781-28903071 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 64807
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;6 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: DHRS13
• Gene Tree
  Dhrs13
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Targeted
  1
• Genomic Mutations
  2 involving Dhrs13
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  6 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  20
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase dhrs13

Interactions

• Dhrs13 interacts with 159 markers (Mir10a, Mir15a, Mir15b, ...) View All

Sequences &
Gene Models

• All Sequences
  40
• RefSeq
  2
• UniProt
  4
• CCDS
  CCDS36236.1
• UniGene
  390342

• Ensembl
  ENSMUSG00000020834 (Evidence)
• NCBI Gene
  70451

Representative Sequences			Length	Strain/Species
genomic	70451	NCBI Gene Model | MGI Sequence Detail	5552	C57BL/6J
transcript	NM_183286	RefSeq | MGI Sequence Detail	1744	C57BL/6
polypeptide	Q5SS80	UniProt | EBI | MGI Sequence Detail	376	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000006463 dehydrogenase/reductase SDR family member 13
  (term hierarchy)
• EC
  1.1.-.-
• InterPro Domains
  IPR036291 NAD(P)-binding domain superfamily
  IPR002347 Short-chain dehydrogenase/reductase SDR

Molecular
Reagents

• All nucleic 20

  cDNA 20

  
  

  Microarray probesets 4

References

• Summaries
  All 28

  Developmental Gene Expression 1

  Gene Ontology 1

  Phenotypes 8
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

TSS for Dhrs13:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr103213	Chr11:78032274-78032310 (+)	-21 bp
Tssr103214	Chr11:78032312-78032343 (+)	15 bp
Tssr103215	Chr11:78032346-78032366 (+)	43 bp