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Taf15
Gene Detail
Symbol

Name
ID
Taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
MGI:1917689
Synonyms
2610111C21Rik, 68kDa, Taf2n, TAFII68
Feature Type
protein coding gene
Genetic Map
Chromosome 11
50.49 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:83473086-83506743 bp, + strand
From VEGA annotation of GRCm38

  33658 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:131088  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 chicken; 1 western clawed frog

HCOP human homology predictions: TAF15
Protein SuperFamily: RNA-binding protein, EWS type
Gene Tree: Taf15

Human
homologs
TAF15, TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8148
neXtProt AC: NX_Q92804

Human Synonyms: Npl3, RBP56, TAF2N, TAFII68

Human Chr (Location): 17q11.1-q11.2; chr17:35809455-35847242 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TAF15

Mutations,
alleles, and
phenotypes
All mutations/alleles(35) : Gene trapped(32) Targeted(3)
Genomic Mutations involving Taf15 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Taf15 interacts with 54 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process biological_process
Component cytoplasm, nucleoplasm, ...
Function poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (57)    Tissues (48)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 45
Western blot 10
RT-PCR 2
cDNA source data(35)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA TAF15 ; Xenbase taf15    NEW 
Molecular
reagents
All nucleic(39) Genomic(1) cDNA(37) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000000917 (Evidence)
Ensembl Gene Model ENSMUSG00000020680 (Evidence)
Entrez Gene 70439 (Evidence)
UniGene 181050
DFCI TC1619534, TC1600726, TC1582966, TC1599626
DoTS DT.40135572, DT.101163027, DT.40162341, DT.40166404
NIA Mouse Gene Index U013090
Consensus CDS Project CCDS25168.1
International Mouse Phenotyping Consortium Status Taf15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000917 VEGA Gene Model | MGI Sequence Detail 33658 C57BL/6J ±  kb
transcript OTTMUST00000001784 VEGA | MGI Sequence Detail 2068 Not Applicable 
polypeptide OTTMUSP00000000854 VEGA | MGI Sequence Detail 557 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(12) UniProt(4)
Polymorphisms
SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
InterPro IPR001876 Zinc finger, RanBP2-type
Protein Ontology PR:000016019 TATA-binding protein-associated factor 2N
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory