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Taf15 Gene Detail
Summary
  • Symbol
    Taf15
  • Name
    TATA-box binding protein associated factor 15
  • Synonyms
    2610111C21Rik, 68kDa, Taf2n, TAFII68
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917689
    NCBI Gene: 70439
  • Gene Overview
    MyGene.info: TAF15
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83473086-83506743 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 50.49 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917689
protein coding gene Chr11:83473068-83506743 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018850
protein coding gene Chr11:84796648-84839017 (+)
A/J MGP_AJ_G0018817
protein coding gene Chr11:81583465-81616888 (+)
AKR/J MGP_AKRJ_G0018787
protein coding gene Chr11:84008517-84057530 (+)
BALB/cJ MGP_BALBcJ_G0018790
protein coding gene Chr11:81994262-82027289 (+)
C3H/HeJ MGP_C3HHeJ_G0018604
protein coding gene Chr11:84068394-84103387 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019242
protein coding gene Chr11:87394328-87432947 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016876
protein coding gene Chr11:78710134-78745513 (+)
CAST/EiJ MGP_CASTEiJ_G0018159
protein coding gene Chr11:84644173-84688451 (+)
CBA/J MGP_CBAJ_G0018575
protein coding gene Chr11:91176773-91212570 (+)
DBA/2J MGP_DBA2J_G0018683
protein coding gene Chr11:81179728-81217304 (+)
FVB/NJ MGP_FVBNJ_G0018672
protein coding gene Chr11:80662481-80700793 (+)
LP/J MGP_LPJ_G0018753
protein coding gene Chr11:85360422-85397047 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0019282
protein coding gene Chr11:84281205-84320396 (+)
PWK/PhJ MGP_PWKPhJ_G0017928
protein coding gene Chr11:81940933-81975497 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017720
protein coding gene Chr11:83818791-83856346 (+)
WSB/EiJ MGP_WSBEiJ_G0018210
protein coding gene Chr11:84144106-84181984 (+)



Homology
more
  • Human Ortholog
    TAF15, TATA-box binding protein associated factor 15
  • Vertebrate Orthologs
    6
  • Human Ortholog
    TAF15, TATA-box binding protein associated factor 15
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Npl3, RBP56, TAF2N, TAFII68
  • Links
    NCBI Gene ID: 8148
    neXtProt AC: NX_Q92804
    UniProt: Q92804

  • Chr Location
    17q12; chr17:35809455-35847242 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human TAF15 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020680 Ensembl Gene Model | MGI Sequence Detail 33658 C57BL/6J ±  kb
transcript ENSMUST00000021018 Ensembl | MGI Sequence Detail 2068 Not Applicable  
polypeptide ENSMUSP00000021018 Ensembl | MGI Sequence Detail 557 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
    IPR034870 TAF15/EWS/TLS family
    IPR034875 TATA binding associated factor 15
    IPR001876 Zinc finger, RanBP2-type
    IPR036443 Zinc finger, RanBP2-type superfamily
Molecular
Reagents
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  • All nucleic 40
    Genomic 1
    cDNA 38
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 49
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:243043 Svetoni F, et al., Post-transcriptional regulation of FUS and EWS protein expression by miR-141 during neural differentiation. Hum Mol Genet. 2017 Jul 15;26(14):2732-2746

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory