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Polr3b
Gene Detail
Symbol

Name
ID
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
MGI:1917678
Synonyms
2700078H01Rik, A330032P03Rik, RPC2
Feature Type
protein coding gene
Genetic Map
Chromosome 10
41.58 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:84622437-84727177 bp, + strand
From Ensembl annotation of GRCm38

  104741 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6981  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: POLR3B
Protein SuperFamily: DNA-directed RNA polymerase 132K polypeptide
Gene Tree: Polr3b

Human
homologs
POLR3B, polymerase (RNA) III (DNA directed) polypeptide B
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 55703
neXtProt AC: NX_Q9NW08

Human Synonyms: C128, HLD8, INMAP, RPC2

Human Chr (Location): 12q23.3; chr12:106357658-106510198 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human POLR3B

Mutations,
alleles, and
phenotypes
All mutations/alleles(52) : Gene trapped(50) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr3b interacts with 199 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(73)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA POLR3B ; Xenbase polr3b ; ZFIN polr3b    NEW 
Molecular
reagents
All nucleic(73) cDNA(73)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000034453 (Evidence)
Entrez Gene 70428 (Evidence)
UniGene 335007
DFCI TC1578731
DoTS DT.91398370, DT.487531, DT.94227807
NIA Mouse Gene Index U011826
EC 2.7.7.6
Consensus CDS Project CCDS24081.1
International Mouse Phenotyping Consortium Status Polr3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034453 Ensembl Gene Model | MGI Sequence Detail 104741 C57BL/6J ±  kb
transcript ENSMUST00000077175 Ensembl | MGI Sequence Detail 4829 Not Applicable 
polypeptide ENSMUSP00000076418 Ensembl | MGI Sequence Detail 1133 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(3) UniProt(3)
Polymorphisms
SNPs within 2kb(935 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015712 DNA-directed RNA polymerase, subunit 2
InterPro IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6
InterPro IPR007121 RNA polymerase, beta subunit, conserved site
InterPro IPR007644 RNA polymerase, beta subunit, protrusion
InterPro IPR007642 RNA polymerase Rpb2, domain 2
InterPro IPR007645 RNA polymerase Rpb2, domain 3
InterPro IPR007646 RNA polymerase Rpb2, domain 4
InterPro IPR007647 RNA polymerase Rpb2, domain 5
InterPro IPR007641 RNA polymerase Rpb2, domain 7
InterPro IPR014724 RNA polymerase Rpb2, OB-fold
Protein Ontology PR:000013001 DNA-directed RNA polymerase III subunit RPC2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGI:2143941, MGI:2443266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory