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Polr3b
Gene Detail
 Symbol
Name
ID
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
MGI:1917678
Synonyms 2700078H01Rik, A330032P03Rik, RPC2
Feature Type protein coding gene
Genetic Map
Chromosome 10
41.58 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:84622437-84727177 bp, + strand
From Ensembl annotation of GRCm38

  104741 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6981  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: DNA-directed RNA polymerase 132K polypeptide
Gene Tree: Polr3b

Human
homologs
Human Homolog POLR3B, polymerase (RNA) III (DNA directed) polypeptide B
NCBI Gene ID 55703
neXtProt AC  NX_Q9NW08
Human Synonyms  C128, HLD8, RPC2
Human Chr (Location)  12q23.3; chr12:106357658-106510198 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human POLR3B
Mutations,
alleles, and
phenotypes
All mutations/alleles(52) : Gene trapped(50) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr3b interacts with 200 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process defense response to virus, immune system process, ...
Component DNA-directed RNA polymerase III complex, nucleus
Function DNA binding, DNA-directed RNA polymerase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(73)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(73) cDNA(73)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000034453 (Evidence)
Entrez Gene70428 (Evidence)
UniGene335007
DFCITC1578731
DoTSDT.487531, DT.91398370, DT.94227807
NIA Mouse Gene IndexU011826
EC2.7.7.6
Consensus CDS ProjectCCDS24081.1
International Mouse Knockout Project StatusPolr3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034453 Ensembl Gene Model | MGI Sequence Detail 104741 C57BL/6J ±  kb
transcript ENSMUST00000077175 Ensembl | MGI Sequence Detail 4829 Not Applicable 
polypeptide ENSMUSP00000076418 Ensembl | MGI Sequence Detail 1133 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(3) UniProt(3)
Polymorphisms SNPs within 2kb(935 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015712 DNA-directed RNA polymerase, subunit 2
InterPro IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6
InterPro IPR007121 RNA polymerase, beta subunit, conserved site
InterPro IPR007644 RNA polymerase, beta subunit, protrusion
InterPro IPR007642 RNA polymerase Rpb2, domain 2
InterPro IPR007645 RNA polymerase Rpb2, domain 3
InterPro IPR007646 RNA polymerase Rpb2, domain 4
InterPro IPR007647 RNA polymerase Rpb2, domain 5
InterPro IPR007641 RNA polymerase Rpb2, domain 7
InterPro IPR014724 RNA polymerase Rpb2, OB-fold
Protein Ontology PR:000013001 DNA-directed RNA polymerase III subunit RPC2
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)
Other
accession IDs
MGI:2143941, MGI:2443266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory