Polr3b
Gene Detail

Symbol Name ID

Polr3b polymerase (RNA) III (DNA directed) polypeptide B MGI:1917678

Synonyms

2700078H01Rik, A330032P03Rik, RPC2

Feature Type

protein coding gene

Genetic Map

Chromosome 10

41.58 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr10:84622437-84727177 bp, + strand From Ensembl annotation of GRCm38   104741 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:6981  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: DNA-directed RNA polymerase 132K polypeptide
Gene Tree: Polr3b

Human homologs

Human Homolog		POLR3B, polymerase (RNA) III (DNA directed) polypeptide B
NCBI Gene ID		55703
neXtProt AC		NX_Q9NW08
Human Synonyms		C128, HLD8, RPC2
Human Chr (Location)		12q23.3; chr12:106751436-106903976 (+)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human POLR3B

Alleles and phenotypes

All alleles(52) : Targeted(2) Gene trapped(50)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	defense response to virus, innate immune response, ...
Component	nucleus
Function	DNA binding, DNA-directed RNA polymerase activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(72)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(72) cDNA(72)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000034453 (Evidence)
Entrez Gene	70428 (Evidence)
UniGene	335007
DFCI	TC1578731
DoTS	DT.487531, DT.91398370, DT.94227807
NIA Mouse Gene Index	U011826
EC	2.7.7.6
Consensus CDS Project	CCDS24081.1
International Mouse Knockout Project Status	Polr3b

Sequences

Length	Strain/Species
genomic	ENSMUSG00000034453	Ensembl Gene Model | MGI Sequence Detail	104741	C57BL/6J
transcript	ENSMUST00000077175	Ensembl | MGI Sequence Detail	4829	Not Applicable
polypeptide	ENSMUSP00000076418	Ensembl | MGI Sequence Detail	1133	Not Applicable

All sequences(23) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(697 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015712	DNA-directed RNA polymerase, subunit 2
InterPro	IPR007120	DNA-directed RNA polymerase, subunit 2, domain 6
InterPro	IPR007121	RNA polymerase, beta subunit, conserved site
InterPro	IPR007644	RNA polymerase, beta subunit, protrusion
InterPro	IPR007642	RNA polymerase Rpb2, domain 2
InterPro	IPR007645	RNA polymerase Rpb2, domain 3
InterPro	IPR007646	RNA polymerase Rpb2, domain 4
InterPro	IPR007647	RNA polymerase Rpb2, domain 5
InterPro	IPR007641	RNA polymerase Rpb2, domain 7
InterPro	IPR014724	RNA polymerase Rpb2, OB-fold
Protein Ontology	PR:000013001	DNA-directed RNA polymerase III subunit RPC2

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)

Other accession IDs

MGI:2143941, MGI:2443266