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Ints2
Gene Detail
Symbol

Name
ID
Ints2
integrator complex subunit 2
MGI:1917672
Synonyms
2810417D08Rik, mKIAA1287
Feature Type
protein coding gene
Genetic Map
Chromosome 11
51.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:86210681-86257575 bp, - strand
From VEGA annotation of GRCm38

  46895 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10801  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: INTS2
Gene Tree: Ints2

Human
homologs
INTS2, integrator complex subunit 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 57508
neXtProt AC: NX_Q9H0H0

Human Synonyms: INT2, KIAA1287

Human Chr (Location): 17q23.2; chr17:61865367-61928030 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(7) Targeted(3)
Genomic Mutations involving Ints2 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ints2 interacts with 306 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process snRNA processing
Component integral component of membrane, integrator complex, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ints2 ; ZFIN ints2    NEW 
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000001206 (Evidence)
Ensembl Gene Model ENSMUSG00000018068 (Evidence)
Entrez Gene 70422 (Evidence)
DFCI TC1618797, TC1589209, TC1578715
NIA Mouse Gene Index U033220
Consensus CDS Project CCDS25198.1
International Mouse Phenotyping Consortium Status Ints2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001206 VEGA Gene Model | MGI Sequence Detail 46895 C57BL/6J ±  kb
transcript OTTMUST00000002408 VEGA | MGI Sequence Detail 5906 Not Applicable 
polypeptide OTTMUSP00000001185 VEGA | MGI Sequence Detail 1198 Not Applicable 

For the selected sequences
All sequences(92) RefSeq(27) UniProt(7)
Polymorphisms
SNPs within 2kb(170 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026236 Integrator complex subunit 2
Protein Ontology PR:000009069 integrator complex subunit 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)
Other
accession IDs
MGI:2143979, MGI:2144333

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory