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Arpin Gene Detail
Summary
  • Symbol
    Arpin
  • Name
    actin-related protein 2/3 complex inhibitor
  • Synonyms
    2610034B18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917670
    NCBI Gene: 70420
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:79925359-79935264 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 45.27 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    53 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917670
protein coding gene Chr7:79925359-79935359 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032400
protein coding gene Chr7:81842615-81852028 (-)
A/J MGP_AJ_G0032379
protein coding gene Chr7:79953629-79963135 (-)
AKR/J MGP_AKRJ_G0032315
protein coding gene Chr7:81670524-81683626 (-)
BALB/cJ MGP_BALBcJ_G0032391
protein coding gene Chr7:79637055-79646598 (-)
C3H/HeJ MGP_C3HHeJ_G0032104
protein coding gene Chr7:82323611-82333130 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032883
protein coding gene Chr7:85052484-85065091 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029891
protein coding gene Chr7:82479048-82487709 (-)
CAST/EiJ MGP_CASTEiJ_G0031432
protein coding gene Chr7:73195935-73206948 (-)
CBA/J MGP_CBAJ_G0032070
protein coding gene Chr7:87893197-87905053 (-)
DBA/2J MGP_DBA2J_G0032225
protein coding gene Chr7:78510388-78520488 (-)
FVB/NJ MGP_FVBNJ_G0032180
protein coding gene Chr7:78423171-78436695 (-)
LP/J MGP_LPJ_G0032306
protein coding gene Chr7:83096609-83107108 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032217
protein coding gene Chr7:88054947-88066149 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032901
protein coding gene Chr7:81113621-81124389 (-)
PWK/PhJ MGP_PWKPhJ_G0031152
protein coding gene Chr7:71690847-71702240 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030993
protein coding gene Chr7:68114165-68126754 (-)
WSB/EiJ MGP_WSBEiJ_G0031550
protein coding gene Chr7:81432802-81444366 (-)



Homology
more
  • Human Ortholog
    ARPIN, actin related protein 2/3 complex inhibitor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARPIN, actin related protein 2/3 complex inhibitor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C15orf38
  • Links
    NCBI Gene ID: 348110
    neXtProt AC: NX_Q7Z6K5
    UniProt: Q7Z6K5

  • Chr Location
    15q26.1; chr15:89896532-89912990 (-)  GRCh38.p7

  • Human Ortholog
    C15orf38-AP3S2, C15orf38-AP3S2 readthrough
    Orthology source: HomoloGene
  • Synonyms
    ARPIN, C15orf38
  • Links
    NCBI Gene ID: 100526783

  • Chr Location
    15q26.1; chr15:89830599-89912990 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Arpin
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70420 NCBI Gene Model | MGI Sequence Detail 9906 C57BL/6J ±  kb
transcript NM_027420 RefSeq | MGI Sequence Detail 2184 C57BL/6  
polypeptide Q9D0A3 UniProt | EBI | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018889 Arpin
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:202749 Dang I, et al., Inhibitory signalling to the Arp2/3 complex steers cell migration. Nature. 2013 Nov 14;503(7475):281-4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory