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Arpin Gene Detail
Summary
  • Symbol
    Arpin
  • Name
    actin-related protein 2/3 complex inhibitor
  • Synonyms
    2610034B18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917670
    NCBI Gene: 70420
Location & Maps
more
  • Sequence Map
    Chr7:79925361-79935359 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9999 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 45.27 cM, cytoband D2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ARPIN, actin-related protein 2/3 complex inhibitor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARPIN, actin-related protein 2/3 complex inhibitor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C15orf38
  • Links
    NCBI Gene ID: 348110
    neXtProt AC: NX_Q7Z6K5

  • Chr Location
    15q26.1; chr15:89896532-89912990 (-)  GRCh38.p2

  • Human Ortholog
    C15orf38-AP3S2, C15orf38-AP3S2 readthrough
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 100526783

  • Chr Location
    15q; chr15:89830599-89912990 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Arpin
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023196 VEGA Gene Model | MGI Sequence Detail 9999 C57BL/6J ±  kb
transcript OTTMUST00000056119 VEGA | MGI Sequence Detail 2277 Not Applicable  
polypeptide OTTMUSP00000026929 VEGA | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    53 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018889 Uncharacterised protein family UPF0552
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 17
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202749 Dang I, et al., Inhibitory signalling to the Arp2/3 complex steers cell migration. Nature. 2013 Nov 14;503(7475):281-4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory