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Asnsd1 Gene Detail
Summary
  • Symbol
    Asnsd1
  • Name
    asparagine synthetase domain containing 1
  • Synonyms
    2210409M21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917646
    NCBI Gene: 70396
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr1:53383776-53391911 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 26.99 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917646
protein coding gene Chr1:53383776-53391911 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016021
protein coding gene Chr1:52889278-52897964 (-)
A/J MGP_AJ_G0016003
protein coding gene Chr1:51104375-51112522 (-)
AKR/J MGP_AKRJ_G0015959
protein coding gene Chr1:52222340-52230474 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0015791
protein coding gene Chr1:52601602-52610457 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016411
protein coding gene Chr1:55067451-55077017 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014113
protein coding gene Chr1:40776633-40784898 (+)
CAST/EiJ MGP_CASTEiJ_G0015373
protein coding gene Chr1:52090369-52098527 (-)
CBA/J MGP_CBAJ_G0015762
protein coding gene Chr1:56578282-56586054 (-)
DBA/2J MGP_DBA2J_G0015864
protein coding gene Chr1:50378043-50387678 (-)
FVB/NJ MGP_FVBNJ_G0015866
protein coding gene Chr1:49835646-49843781 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0015886
protein coding gene Chr1:59651688-59659863 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016459
protein coding gene Chr1:52338378-52347081 (-)
PWK/PhJ MGP_PWKPhJ_G0015159
protein coding gene Chr1:50227265-50237997 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014939
protein coding gene Chr1:51997001-52005155 (-)
WSB/EiJ MGP_WSBEiJ_G0015436
protein coding gene Chr1:52141608-52149739 (-)



Homology
more
  • Human Ortholog
    ASNSD1, asparagine synthetase domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASNSD1, asparagine synthetase domain containing 1
  • Synonyms
    NBLA00058, NS3TP1
  • Links
    NCBI Gene ID: 54529
    neXtProt AC: NX_Q9NWL6
    UniProt: Q9NWL6

  • Chr Location
    2q32.2; chr2:189661385-189670831 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Asnsd1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Mice homozygous for a null allele exhibit partial preweaning lethality and handling-associated seizures and develop a progressive degenerative myopathy with severe muscle weakness and myosteatosis but no signs of lipotoxicity despite their extremely increased body fat percentage and low skeletal muscle mass.
Gene Ontology
(GO)
Classifications
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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70396 NCBI Gene Model | MGI Sequence Detail 8136 C57BL/6J ±  kb
transcript NM_133728 RefSeq | MGI Sequence Detail 2450 C57BL/6  
polypeptide Q8BFS9 UniProt | EBI | MGI Sequence Detail 627 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 133
    cDNA 133

    Microarray probesets 5
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory