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Spdl1 Gene Detail
Summary
  • Symbol
    Spdl1
  • Name
    spindle apparatus coiled-coil protein 1
  • Synonyms
    1700018I02Rik, 2600001J17Rik, 2810049B11Rik, Ccdc99
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917635
    NCBI Gene: 70385
Location & Maps
more
  • Sequence Map
    Chr11:34809190-34833641 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24452 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 19.90 cM, cytoband A5
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SPDL1, spindle apparatus coiled-coil protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SPDL1, spindle apparatus coiled-coil protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCDC99
  • Links
    NCBI Gene ID: 54908
    neXtProt AC: NX_Q96EA4

  • Chr Location
    5q35.1; chr5:169583634-169604778 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9837
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SPDL1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Spdl1
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008080 VEGA Gene Model | MGI Sequence Detail 24452 C57BL/6J ±  kb
transcript OTTMUST00000018344 VEGA | MGI Sequence Detail 2505 Not Applicable  
polypeptide OTTMUSP00000008436 VEGA | MGI Sequence Detail 608 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    123 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029767 protein Spindly
  • InterPro Domains
    IPR028593 Protein Spindly, chordates
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 2
Other
Accession IDs
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MGI:1919953, MGI:1923654, MGI:2144000
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory