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Cox10 Gene Detail
Summary
  • Symbol
    Cox10
  • Name
    heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
  • Synonyms
    2410004F01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917633
    NCBI Gene: 70383
  • Gene Overview
    MyGene.info: COX10
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:63962627-64079468 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 39.47 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    889 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917633
protein coding gene Chr11:63962627-64079472 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018470
protein coding gene Chr11:64101944-64224557 (-)
A/J MGP_AJ_G0018439
protein coding gene Chr11:61712486-61835042 (-)
AKR/J MGP_AKRJ_G0018408
protein coding gene Chr11:63625102-63750237 (-)
BALB/cJ MGP_BALBcJ_G0018410
protein coding gene Chr11:61985174-62102890 (-)
C3H/HeJ MGP_C3HHeJ_G0018223
protein coding gene Chr11:63585597-63704502 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018862
protein coding gene Chr11:66070069-66196618 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016506
protein coding gene Chr11:58764252-58882393 (-)
CAST/EiJ MGP_CASTEiJ_G0017779
protein coding gene Chr11:63755996-63895471 (-)
CBA/J MGP_CBAJ_G0018197
protein coding gene Chr11:68969602-69088901 (-)
DBA/2J MGP_DBA2J_G0018306
protein coding gene Chr11:61274154-61394853 (-)
FVB/NJ MGP_FVBNJ_G0018296
protein coding gene Chr11:60925644-61043009 (-)
LP/J MGP_LPJ_G0018378
protein coding gene Chr11:64633357-64758673 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018320
protein coding gene Chr11:69892218-70024831 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018903
protein coding gene Chr11:63789624-63906242 (-)
PWK/PhJ MGP_PWKPhJ_G0017553
protein coding gene Chr11:61863446-62004289 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017343
protein coding gene Chr11:63638693-63764383 (-)
WSB/EiJ MGP_WSBEiJ_G0017832
protein coding gene Chr11:63403717-63522654 (-)



Homology
more
  • Human Ortholog
    COX10, cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COX10, cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 1352
    neXtProt AC: NX_Q12887
    UniProt: Q12887

  • Chr Location
    17p12; chr17:14069402-14208679 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    3 with Cox10 mouse models; 2 with human COX10 associations

Human Disease Mouse Models
      
IDs
View 1 model
      
IDs
View 1 model
IDs
View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotypes from 1 allele in 3 genetic backgrounds
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042148 Ensembl Gene Model | MGI Sequence Detail 116842 C57BL/6J ±  kb
    transcript ENSMUST00000049091 Ensembl | MGI Sequence Detail 2915 Not Applicable  
    polypeptide ENSMUSP00000040138 Ensembl | MGI Sequence Detail 443 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 46
      cDNA 44
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144433
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 2
      Diseases 3
      Gene Ontology 9
      Phenotypes 24
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:263026 Chen Q, et al., Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations. Cell Metab. 2018 May 1;27(5):1007-1025.e5

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory