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Kctd2 Gene Detail
Summary
  • Symbol
    Kctd2
  • Name
    potassium channel tetramerisation domain containing 2
  • Synonyms
    2310012I15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917632
    NCBI Gene: 70382
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115420128-115431274 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    53 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917632
protein coding gene Chr11:115420076-115431274 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019386
protein coding gene Chr11:119441492-119454769 (+)
A/J MGP_AJ_G0019355
protein coding gene Chr11:114227163-114238639 (+)
AKR/J MGP_AKRJ_G0019325
protein coding gene Chr11:117634556-117645773 (+)
BALB/cJ MGP_BALBcJ_G0019329
protein coding gene Chr11:114640717-114651911 (+)
C3H/HeJ MGP_C3HHeJ_G0019135
protein coding gene Chr11:117985533-117998798 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019779
protein coding gene Chr11:123083702-123094848 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017402
protein coding gene Chr11:111266389-111277781 (+)
CAST/EiJ MGP_CASTEiJ_G0018690
protein coding gene Chr11:119298184-119310861 (+)
CBA/J MGP_CBAJ_G0019107
protein coding gene Chr11:127936895-127950160 (+)
DBA/2J MGP_DBA2J_G0019218
protein coding gene Chr11:113663062-113674239 (+)
FVB/NJ MGP_FVBNJ_G0019210
protein coding gene Chr11:113138628-113149812 (+)
LP/J MGP_LPJ_G0019288
protein coding gene Chr11:119827466-119839234 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019243
protein coding gene Chr11:127112442-127125718 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019817
protein coding gene Chr11:118290275-118301756 (+)
PWK/PhJ MGP_PWKPhJ_G0018454
protein coding gene Chr11:114945688-114956899 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018247
protein coding gene Chr11:118036608-118047568 (+)
WSB/EiJ MGP_WSBEiJ_G0018742
protein coding gene Chr11:118239291-118250491 (+)



Homology
more
  • Human Ortholog
    KCTD2, potassium channel tetramerization domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCTD2, potassium channel tetramerization domain containing 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23510
    neXtProt AC: NX_Q14681
    UniProt: Q14681

  • Chr Location
    17q25.1; chr17:75032567-75065889 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 82389
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KCTD2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016940 Ensembl Gene Model | MGI Sequence Detail 11147 C57BL/6J ±  kb
transcript ENSMUST00000106533 Ensembl | MGI Sequence Detail 2649 Not Applicable  
polypeptide ENSMUSP00000102143 Ensembl | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR011333 SKP1/BTB/POZ domain superfamily
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 4
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:195239 Ahmed SM, et al., KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. J Cell Biol. 2012 Dec 10;199(6):951-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory