Fam114a2 Gene Detail

Summary

• Symbol
  Fam114a2
• Name
  family with sequence similarity 114, member A2
• Synonyms
  1810073G14Rik, 9030624B09Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1917629
  NCBI Gene: 67726
• Gene Overview
  MyGene.info: FAM114A2
• Alliance
  gene page
• Transcription Start Sites
  5 TSS

Location &
Maps

• Sequence Map
  Chr11:57482993-57518617 bp, - strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 35.27 cM, cytoband B2
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  412 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917629	protein coding gene	Chr11:57482990-57518656 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0018336	protein coding gene	Chr11:57098178-57134484 (-)
A/J	MGP_AJ_G0018305	protein coding gene	Chr11:54955310-54990295 (-)
AKR/J	MGP_AKRJ_G0018274	protein coding gene	Chr11:56765380-56800109 (-)
BALB/cJ	MGP_BALBcJ_G0018276	protein coding gene	Chr11:55296087-55330467 (-)
C3H/HeJ	MGP_C3HHeJ_G0018088	protein coding gene	Chr11:56683186-56719300 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0018728	protein coding gene	Chr11:58838941-58877751 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016378	protein coding gene	Chr11:52324806-52361309 (-)
CAST/EiJ	MGP_CASTEiJ_G0017652	protein coding gene	Chr11:56741397-56777297 (-)
CBA/J	MGP_CBAJ_G0018062	protein coding gene	Chr11:61565863-61607183 (-)
DBA/2J	MGP_DBA2J_G0018171	protein coding gene	Chr11:54605403-54640683 (-)
FVB/NJ	MGP_FVBNJ_G0018163	protein coding gene	Chr11:54288572-54323197 (-)
LP/J	MGP_LPJ_G0018246	protein coding gene	Chr11:57580995-57618069 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018189	protein coding gene	Chr11:62711131-62749838 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018770	protein coding gene	Chr11:56770784-56807253 (-)
PWK/PhJ	MGP_PWKPhJ_G0017425	protein coding gene	Chr11:55209717-55246502 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0017220	protein coding gene	Chr11:56651949-56688219 (-)
WSB/EiJ	MGP_WSBEiJ_G0017700	protein coding gene	Chr11:56424313-56458684 (-)

Homology

• Human Ortholog
  FAM114A2, family with sequence similarity 114 member A2

• Vertebrate Orthologs
  9

• Human Ortholog
  FAM114A2, family with sequence similarity 114 member A2
  Orthology source: HomoloGene, HGNC
• Synonyms
  133K02, C5orf3
• Links
  HGNC:1333

  NCBI Gene ID: 10827

  neXtProt AC: NX_Q9NRY5

  UniProt: Q9NRY5

  
  
• Chr Location
  5q33.2; chr5:153990131-154038938 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 10270
  1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: FAM114A2
• Gene Tree
  Fam114a2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  10
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Gene trapped
  6
• Targeted
  2
• Genomic Mutations
  1 involving Fam114a2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  15 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• Assay Results
  110
• Tissues
  94
• cDNA Data
  121
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase fam114a2

Interactions

• Fam114a2 interacts with 163 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  65
• RefSeq
  22
• UniProt
  1
• CCDS
  CCDS24717.1, CCDS48801.1
• UniGene
  25632

• Ensembl
  ENSMUSG00000020523 (Evidence)
• NCBI Gene
  67726

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000020523	Ensembl Gene Model | MGI Sequence Detail	35625	C57BL/6J
transcript	ENSMUST00000108850	Ensembl | MGI Sequence Detail	1765	Not Applicable
polypeptide	ENSMUSP00000104478	Ensembl | MGI Sequence Detail	497	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000031699 protein FAM114A2
  (term hierarchy)
• InterPro Domains
  IPR007998 Protein of unknown function DUF719

Molecular
Reagents

• All nucleic 122

  cDNA 121

  Other 1

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:1914976

References

• Summaries
  All 31

  Developmental Gene Expression 2

  Phenotypes 7
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Fam114a2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr108117	Chr11:57518596-57518655 (-)	-9 bp
Tssr108116	Chr11:57507129-57507134 (-)	11,485 bp
Tssr108115	Chr11:57507110-57507115 (-)	11,504 bp
Tssr108114	Chr11:57507102-57507106 (-)	11,513 bp
Tssr108113	Chr11:57507041-57507052 (-)	11,570 bp