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Bag5 Gene Detail
Summary
  • Symbol
    Bag5
  • Name
    BCL2-associated athanogene 5
  • Synonyms
    1600025G07Rik, 4930405J06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917619
    NCBI Gene: 70369
  • Gene Overview
    MyGene.info: BAG5
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:111709488-111713257 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 61.11 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917619
protein coding gene Chr12:111709488-111713317 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020139
protein coding gene Chr12:114112836-114116604 (-)
A/J MGP_AJ_G0020095
protein coding gene Chr12:109732218-109735966 (-)
AKR/J MGP_AKRJ_G0020070
protein coding gene Chr12:112873057-112876805 (-)
BALB/cJ MGP_BALBcJ_G0020080
protein coding gene Chr12:110156046-110159812 (-)
C3H/HeJ MGP_C3HHeJ_G0019882
protein coding gene Chr12:113374785-113378533 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020525
protein coding gene Chr12:117660104-117663871 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018138
protein coding gene Chr12:106170769-106174539 (-)
CAST/EiJ MGP_CASTEiJ_G0019423
protein coding gene Chr12:108217670-108221427 (-)
CBA/J MGP_CBAJ_G0019849
protein coding gene Chr12:122128422-122132170 (-)
DBA/2J MGP_DBA2J_G0019966
protein coding gene Chr12:109208709-109212457 (-)
FVB/NJ MGP_FVBNJ_G0019951
protein coding gene Chr12:108015357-108019106 (-)
LP/J MGP_LPJ_G0020041
protein coding gene Chr12:113939061-113942827 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019989
protein coding gene Chr12:125266536-125270284 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020554
protein coding gene Chr12:112393381-112397130 (-)
PWK/PhJ MGP_PWKPhJ_G0019184
protein coding gene Chr12:103853978-103858241 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018987
protein coding gene Chr12:106562269-106566030 (-)
WSB/EiJ MGP_WSBEiJ_G0019482
protein coding gene Chr12:113304031-113307779 (-)



Homology
more
  • Human Ortholog
    BAG5, BCL2 associated athanogene 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BAG5, BCL2 associated athanogene 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAG-5
  • Links
    NCBI Gene ID: 9529
    neXtProt AC: NX_Q9UL15
    UniProt: Q9UL15

  • Chr Location
    14q32.33; chr14:103556544-103562814 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3584
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BAG5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049792 Ensembl Gene Model | MGI Sequence Detail 3770 C57BL/6J ±  kb
transcript ENSMUST00000054636 Ensembl | MGI Sequence Detail 2139 Not Applicable  
polypeptide ENSMUSP00000051049 Ensembl | MGI Sequence Detail 447 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 58

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922041
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:212717 Wang X, et al., BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation. PLoS One. 2014;9(1):e86276

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory